Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.65 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817571 | 0.96 | KCNK3 (0.65) | KCNK3KCNK9RAB9ANPC1HDAC2 | |
| SCHEMBL2911616 | 0.90 | HDAC2 (0.71) | KCNK3KCNK9RAB9ANPC1HDAC2 | |
| SCHEMBL27998305 | 0.88 | KDR (0.64) | KCNK3KCNK9RAB9ANPC1MEN1 | |
| SCHEMBL3786882 | 0.85 | KCNK3 (0.87) | KCNK3KCNK9RAB9ANPC1HDAC2 | |
| SCHEMBL5342089 | 0.84 | MEN1 (0.72) | KCNK3KCNK9RAB9ANPC1MEN1 | |
| SCHEMBL2117869 | 0.82 | PTPN1 (0.71) | KCNK3KCNK9RAB9ANPC1HDAC2 | |
| SCHEMBL8374911 | 0.82 | HDAC1 (0.85) | KCNK3KCNK9RAB9ANPC1HDAC2 | |
| SCHEMBL14715899 | 0.82 | PTPN1 (0.77) | KCNK3KCNK9RAB9ANPC1HDAC2 | |
| SCHEMBL1459180 | 0.81 | MEN1 (0.64) | MEN1KMT2A | |
| SCHEMBL19382699 | 0.81 | HTT (0.60) | KCNK3KCNK9RAB9ANPC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |