Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.87 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.87 |
| ▸ | NPC1 | O15118 | 2/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.67 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.67 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.67 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.67 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675463 | 0.91 | KCNK3 (0.84) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| SCHEMBL3674558 | 0.89 | KCNK3 (0.71) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| SCHEMBL3794687 | 0.89 | NPC1 (1.00) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| SCHEMBL25694006 | 0.89 | KCNK3 (0.80) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| SCHEMBL13802448 | 0.88 | MEN1 (0.78) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| SCHEMBL1811760 | 0.88 | KCNK3 (0.79) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| Iodide SCHEMBL30758613 | 0.88 | NPC1 (0.97) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL2107467 | 0.87 | KCNK3 (0.77) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| SCHEMBL8374911 | 0.87 | HDAC1 (0.85) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| SCHEMBL5046341 | 0.85 | KCNK3 (0.65) | KCNK3KCNK9NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483582-B | Aza-carbene-palladium complex crystal, synthesis method thereof and application thereof in preparing amide compound | 陕西师范大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-115304507-A | Synthesis method of N-substituted aryl formamide | 兰州石化职业技术大学 | 2022-11-08 | — | — | CN | disclosed |
| EP-3187490-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2017-07-05 | — | — | EP | disclosed |
| US-8975288-B2 | F2 derivatives as antibacterial agents | THE PENN STATE RESEARCH FOUNDATION (US) | 2015-03-10 | — | — | US | disclosed |
| US-8975288-B2 | F2 derivatives as antibacterial agents | THE PENN STATE RESEARCH FOUNDATION (US) | 2015-03-10 | — | — | US | disclosed |
| US-20140275192-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | THE PENN STATE RESEARCH FOUNDATION | 2014-09-18 | — | — | US | disclosed |
| US-20140275192-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | THE PENN STATE RESEARCH FOUNDATION | 2014-09-18 | — | — | US | disclosed |
| WO-2013154793-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2013-10-17 | — | — | WO | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| CN-101489988-A | Process for alkenylation of carboxamides | BASF AG (DE) | 2009-07-22 | — | — | CN | disclosed |
| US-7528266-B2 | Chemical intermediates of byproduct-free 7-thio-3H-isobenzofuran-1-one derivatives and herbicidal 7-[(4,6-dimethoxy-pyrimidin-2-yl)thio]-3-methyl-3H-isobenzo-furan-1-one | SYNGENTA CROP PROTECTION, INC. (US) | 2009-05-05 | — | — | US | disclosed |
| US-20080108813-A1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080097111-A1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-7307175-B2 | Process for the preparation of 7-substituted 3-alkyl-3H-isobenzofuran-1-one derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2007-12-11 | — | — | US | disclosed |
| EP-1390339-B1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| US-20040158080-A1 | Process for the preparation of 7-substituted 3-alkyl-3h-isobenzofuran-1-one derivatives | SYNGENTA CROP PROTECTION, INC. | 2004-08-12 | — | — | US | disclosed |
| EP-1390339-A2 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | Syngenta Participations AG (CH) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002094760-A2 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-11-28 | — | — | WO | disclosed |
| US-4499167-A | Photoconductive compositions comprising an organic photoconductor and an amide compound and electro-photographic light-sensitive materials using the compositions | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108813-A1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | C1S, CYP2S1, SULT2A1 | KCNK3 506/4885KCNK9 835/4885NPC1 3107/4885 |
| US-20140275192-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | NR2C2, H1-10, NR2F2 | KCNK3 3138/4885KCNK9 1717/4885NPC1 554/4885 |
| US-20080097111-A1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | C1S, C1R, C3AR1 | KCNK3 1072/4885KCNK9 1805/4885NPC1 437/4885 |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | KCNK3 2193/4885KCNK9 2467/4885NPC1 724/4885 |
| US-20040158080-A1 | Process for the preparation of 7-substituted 3-alkyl-3h-isobenzofuran-1-one derivatives | CBR1, AFF1, ALK | KCNK3 1410/4885KCNK9 1443/4885NPC1 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.