Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263975 | 0.93 | TSHR (0.39) | TSHRMAPTCYP3A4ABCC4HSD17B10 | |
| SCHEMBL4452709 | 0.88 | TSHR (0.41) | TSHRMAPTCYP3A4ABCC4ALOX15 | |
| SCHEMBL5447947 | 0.84 | TSHR (0.39) | TSHRMAPTCYP3A4ABCC4ALOX15 | |
| SCHEMBL16618079 | 0.82 | MAPT (0.44) | MAPTCYP3A4ABCC4ALOX15HSD17B10 | |
| SCHEMBL18828 | 0.82 | — | — | |
| SCHEMBL197550 | 0.81 | LMNA (0.32) | TSHRMAPTCYP3A4ABCC4SMN1; SMN2 | |
| SCHEMBL1955290 | 0.81 | MAPT (0.40) | MAPTCYP3A4ABCC4ALOX15HSD17B10 | |
| Fluoride SCHEMBL12006687 | 0.80 | MAPT (0.43) | MAPTCYP3A4ABCC4ALOX15HSD17B10 | |
| SCHEMBL4562517 | 0.80 | MAPT (0.43) | MAPTCYP3A4ABCC4ALOX15HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL1076582 | 0.80 | MAPT (0.43) | MAPTCYP3A4ABCC4ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120027840-A1 | ADHESIVE PATCH AND PATCH PREPARATION | NITTO DENKO CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |