Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043217 | 0.91 | MRGPRX4 (0.41) | MRGPRX4TAAR1GLAPTGER4 | |
| SCHEMBL2769588 | 0.85 | TAS2R14 (0.39) | TAS2R14MRGPRX4TAAR1AKR1C3PLAAT3 | |
| SCHEMBL5727230 | 0.85 | TAS2R14 (0.39) | TAS2R14MRGPRX4TAAR1AKR1C3PLAAT3 | |
| SCHEMBL5726407 | 0.85 | TAS2R14 (0.39) | TAS2R14MRGPRX4TAAR1AKR1C3PLAAT3 | |
| SCHEMBL5726420 | 0.85 | TAS2R14 (0.41) | TAS2R14MRGPRX4TAAR1AKR1C3PLAAT3 | |
| SCHEMBL5046905 | 0.84 | TAS2R14 (0.50) | TAS2R14MRGPRX4AKR1C3PLAAT3PLAAT5 | |
| SCHEMBL5043229 | 0.84 | TAS2R14 (0.40) | TAS2R14MRGPRX4AKR1C3PLAAT3PLAAT5 | |
| SCHEMBL5726679 | 0.84 | CCR5 (0.42) | PTGER1PTGER3MRGPRX4TAAR1GLA | |
| SCHEMBL5725030 | 0.82 | CCR5 (0.41) | PTGER1PTGER3TAAR1PRKG1GLA | |
| SCHEMBL5725567 | 0.82 | TAS2R14 (0.37) | TAS2R14MRGPRX4TAAR1AKR1C3PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442702-B2 | Treatment of bone disorders; carboxy derivatives | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| EP-1021410-B1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER (US) | 2006-12-27 | — | — | EP | disclosed |
| US-6498172-B1 | (3-(((4-TERT-BUTYL-BENZYL)-(PYRIDINE-3-SULFONYL)-AMINO)-METHYL) -PHENOXY)-ACETIC ACID OR SALT; TREATING SUCH AS OSTEOPOROSIS | PFIZER INC. | 2002-12-24 | — | — | US | disclosed |