Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622978 | 0.83 | — | — | |
| SCHEMBL550781 | 0.78 | — | — | |
| SCHEMBL18063240 | 0.76 | OPRM1 (0.46) | OPRM1CA1FDPSTP53LMNA | |
| SCHEMBL28343743 | 0.76 | OPRM1 (0.41) | OPRM1TP53LMNADNM1FFAR1 | |
| SCHEMBL23611409 | 0.74 | OPRM1 (0.39) | OPRM1TP53LMNADNM1SMPD1 | |
| SCHEMBL28434675 | 0.74 | OPRM1 (0.44) | OPRM1FDPSTP53LMNADNM1 | |
| SCHEMBL29126621 | 0.74 | OPRM1 (0.44) | OPRM1FDPSTP53LMNADNM1 | |
| SCHEMBL2927189 | 0.74 | OPRM1 (0.50) | OPRM1TP53LMNA | |
| SCHEMBL28708990 | 0.74 | OPRM1 (0.44) | OPRM1FDPSTP53LMNADNM1 | |
| SCHEMBL6298297 | 0.74 | OPRM1 (0.44) | OPRM1FDPSTP53LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858821-B2 | Method of silica pretreatment | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-01-02 | — | — | US | claimed |
| EP-4023724-A2 | METHOD OF MAKING HYDROPHOBATED SILICA AND USE OF SUCH A SILICA | The Goodyear Tire & Rubber Company (US) | 2022-07-06 | — | — | EP | claimed |
| US-20220204351-A1 | METHOD OF SILICA PRETREATMENT | GOODYEAR TIRE & RUBBER COMPANY, THE | 2022-06-30 | — | — | US | claimed |
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | claimed |
| US-6390163-B1 | BUTADIENE OR ISOPRENE-STYRENE COPOLYMER | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-05-21 | — | — | US | claimed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | claimed |
| US-6053226-A | BLENDING A DIENE BASED ELASTOMER, A REINFROCEMENT FILLER COMPRISED OF PRECIPITATED SILICA AND CARBON BLACK, A PREFORMED COMPOSITE OF MICROCRYSTALLINE WAX, SILICA COUPLING AGENT, ANTIDEGRADANT, VULCANIZATION PROMOTER AND CARBON BLACK | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-04-25 | — | — | US | claimed |
| EP-0764688-B1 | High performance blend for tire treads | GOODYEAR TIRE & RUBBER (US) | 2000-02-23 | — | — | EP | claimed |
| EP-0941872-A2 | Rubber composition reinforced with silica and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-09-15 | — | — | EP | claimed |
| EP-0764688-A1 | High performance blend for tire treads | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | claimed |
| US-5534592-A | POLYBUTADIENE RUBBER BLEND | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-07-09 | — | — | US | claimed |
| US-12043735-B2 | Resin modified oil extended rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240228756-A1 | RUBBER TIRE COMPOUND CONTAINING IPN-PROMOTING RESIN | THE GOODYEAR TIRE & RUBBER COMPANY | 2024-07-11 | — | — | US | disclosed |
| US-11970618-B2 | Rubber tire compound containing IPN-promoting resin | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-04-30 | — | — | US | disclosed |
| US-11912798-B2 | Rubber with backbone and end-group functionalization | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-02-27 | — | — | US | disclosed |
| US-4076550-A | SILICON CONTAINING ORGANO-SILICON COMPOUNDS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1978-02-28 | — | — | US | disclosed |
| US-3997356-A | ORGANO-SILANE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-12-14 | — | — | US | disclosed |
| US-3978103-A | BONDING AGENTS, VULCANIZATION | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-08-31 | — | — | US | disclosed |
| US-3957718-A | Compositions containing silica, a phenoplast or an aminoplast, and a silane | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-05-18 | — | — | US | disclosed |
| US-3938574-A | Vulcanizable rubber mixture for tire treads having improved skid resistance | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022085-A1 | Preparation of surface modified silica | OSTC, SAMM50, SSRP1 | OPRM1 596/4885CA1 447/4885FDPS 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.