Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346405 | 0.80 | PLK1 (0.50) | NR4A1NR4A2NR4A3CDC25BMMP3 | |
| SCHEMBL8074423 | 0.77 | CDC25B (0.56) | NR4A1NR4A2NR4A3CDC25BPTPN1 | |
| SCHEMBL991197 | 0.76 | ERCC5 (0.50) | CYP3A4CYP2C9HPGDKMT2AALDH1A1 | |
| SCHEMBL11300682 | 0.75 | NR4A1 (0.52) | NR4A1NR4A2NR4A3CDC25BMMP3 | |
| SCHEMBL30863852 | 0.75 | NR4A1 (0.69) | NR4A1NR4A2NR4A3CDC25BMMP3 | |
| SCHEMBL1600502 | 0.75 | NR4A1 (0.69) | NR4A1NR4A2NR4A3CDC25BMMP3 | |
| Naphthoic Acid SCHEMBL29352220 | 0.74 | NR4A1 (1.00) | NR4A1NR4A2NR4A3CDC25BMMP3 | |
| Naphthoic Acid SCHEMBL30233567 | 0.74 | NR4A1 (1.00) | NR4A1NR4A2NR4A3CDC25BMMP3 | |
| Naphthoic Acid SCHEMBL17258 | 0.74 | NR4A1 (1.00) | NR4A1NR4A2NR4A3CDC25BMMP3 | |
| Naphthoic Acid SCHEMBL28110155 | 0.74 | NR4A1 (1.00) | NR4A1NR4A2NR4A3CDC25BMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004591-A1 | CYCLOPROPANES WITH CENTRAL NERVOUS SYSTEM ACTIVITY | The Research Foundation Of State University Of New York (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008127223-A1 | CYCLOPROPANES WITH CENTRAL NERVOUS SYSTEM ACTIVITY | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-10-23 | — | — | WO | disclosed |