Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18130355 | 0.82 | NPC1 (0.42) | ERCC5FEN1HPGDMYCALDH1A1 | |
| SCHEMBL28319862 | 0.79 | NPC1 (0.44) | ERCC5FEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL18740870 | 0.78 | STAT3 (0.50) | HPGDALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL5046741 | 0.76 | NR4A1 (0.58) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL28463115 | 0.75 | HPGD (0.40) | ERCC5FEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL2162371 | 0.74 | LMNA (0.50) | ALDH1A1KMT2ACYP2C9CTNNB1WNT3A | |
| SCHEMBL18740988 | 0.74 | HCRTR1 (0.53) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL11299269 | 0.74 | TSHR (0.41) | ERCC5FEN1HPGDMYCKMT2A | |
| SCHEMBL9711362 | 0.74 | ERCC5 (0.57) | ERCC5FEN1HPGDMYCKDM4E | |
| SCHEMBL20564513 | 0.74 | ERCC5 (0.57) | ERCC5FEN1HPGDMYCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025502-A | CATALYTICALLY REACTING AN ARYL HYDRAZONE SUBSTITUTED ACETATE ESTER WITH A NITROGEN HETEROCYCLIC COMPOUND WHICH HAS THE NITROGEN PROTECTED, THEN DEPROTECTING | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-02-15 | — | — | US | claimed |
| US-20110009617-A1 | Ruthenium Catalysts and Uses Thereof | CHE CHI-MING | 2011-01-13 | — | — | US | disclosed |
| US-6025502-A | CATALYTICALLY REACTING AN ARYL HYDRAZONE SUBSTITUTED ACETATE ESTER WITH A NITROGEN HETEROCYCLIC COMPOUND WHICH HAS THE NITROGEN PROTECTED, THEN DEPROTECTING | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009617-A1 | Ruthenium Catalysts and Uses Thereof | CYCS, POR, CPNE4 | ERCC5 4176/4885FEN1 4603/4885HPGD 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.