Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2797070 | 0.91 | KCNH2 (0.45) | KCNH2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12002115 | 0.91 | KCNH2 (0.48) | KCNH2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2796976 | 0.87 | KCNH2 (0.57) | KCNH2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2797074 | 0.84 | KCNH2 (0.47) | KCNH2MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL5040069 | 0.80 | KDM4E (0.43) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2797721 | 0.80 | OPRM1 (0.49) | KCNH2MEN1KMT2AALDH1A1OPRM1 | |
| SCHEMBL2796981 | 0.79 | KCNH2 (0.48) | KCNH2LMNAOPRM1HPGDOPRL1 | |
| SCHEMBL2796712 | 0.77 | KCNH2 (0.46) | KCNH2OPRM1OPRL1OPRD1 | |
| SCHEMBL11968772 | 0.75 | KCNH2 (0.61) | KCNH2ALDH1A1 | |
| SCHEMBL5040333 | 0.74 | KCNH2 (0.58) | KCNH2LMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |
| EP-1900732-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-03-19 | — | — | EP | disclosed |