Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781341 | 0.83 | MCL1 (0.36) | MCL1NOS3NOS1AKR1C3AKR1C2 | |
| SCHEMBL3784454 | 0.79 | SLC6A4 (0.37) | MCL1SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL3799830 | 0.77 | MAOA (0.43) | MCL1SLC6A4HTR2CKMT2A | |
| SCHEMBL14537914 | 0.77 | MCL1 (0.46) | MCL1NOS3NOS1AKR1C3AKR1C2 | |
| SCHEMBL30381395 | 0.77 | MCL1 (0.37) | MCL1NOS3NOS1AKR1C3AKR1C2 | |
| SCHEMBL3786844 | 0.77 | MCL1 (0.37) | MCL1NOS3NOS1AKR1C3AKR1C2 | |
| SCHEMBL389284 | 0.77 | MAPT (0.38) | MCL1NOS3NOS1AKR1C3AKR1C2 | |
| SCHEMBL4544572 | 0.76 | ALDH1A1 (0.54) | MCL1NOS3NOS1MEN1KMT2A | |
| SCHEMBL384929 | 0.75 | MCL1 (0.36) | MCL1NOS3NOS1AKR1C3AKR1C2 | |
| SCHEMBL31379107 | 0.75 | HSD17B10 (0.38) | MCL1GRIN2DGRIN3BSCN1AGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |