Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032983 | 1.00 | AKR1C3 (0.46) | AKR1C3MEN1KMT2AALDH1A1HTT | |
| SCHEMBL7374228 | 0.89 | CDC25B (0.48) | MEN1KMT2AHTTNR4A1NR4A2 | |
| Bromide SCHEMBL7369447 | 0.87 | CDC25B (0.47) | MEN1KMT2AHTTNR4A1NR4A2 | |
| SCHEMBL2149297 | 0.83 | NR4A1 (0.59) | MEN1KMT2AALDH1A1ALOX15NR4A1 | |
| SCHEMBL30430793 | 0.83 | NR4A1 (0.59) | MEN1KMT2AALDH1A1ALOX15NR4A1 | |
| Hydrochloric Acid SCHEMBL4617820 | 0.81 | NR4A1 (0.57) | MEN1KMT2AALDH1A1ALOX15NR4A1 | |
| SCHEMBL30033000 | 0.81 | CES2 (0.41) | CNR2HDAC6 | |
| SCHEMBL30033726 | 0.81 | MEN1 (0.38) | MEN1KMT2AALDH1A1NR4A1NR4A2 | |
| SCHEMBL1121657 | 0.78 | KDM4E (0.50) | KMT2AALDH1A1HTTNR4A1NR4A2 | |
| SCHEMBL8966381 | 0.78 | CYP11B1 (0.43) | MEN1KMT2AALDH1A1NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286572-B | 4-acyl-isoquinoline derivative and preparation method and application thereof | 绍兴文理学院 | 2023-10-13 | — | — | CN | disclosed |
| CN-115286572-A | 4-acyl-isoquinoline derivative and preparation method and application thereof | 绍兴文理学院 | 2022-11-04 | — | — | CN | disclosed |
| US-7361668-B2 | Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors | UCB, S.A. (BE) | 2008-04-22 | — | — | US | disclosed |
| US-20050020660-A1 | Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors | UCB, S.A. (BE) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020660-A1 | Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors | CHRM2, CHRM3, CHRM1 | AKR1C3 291/4885MEN1 2046/4885KMT2A 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.