Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047528 | 1.00 | PPARA (0.52) | PPARAPPARDPPARGTHRBKDM4E | |
| SCHEMBL5047538 | 1.00 | PPARA (0.52) | PPARAPPARDPPARGTHRBKDM4E | |
| SCHEMBL20781163 | 0.91 | PPARA (0.47) | PPARAPPARDPPARGTHRBKDM4E | |
| SCHEMBL25491769 | 0.84 | ALDH1A1 (0.39) | PPARAPPARDPPARGKDM4ELMNA | |
| SCHEMBL25491784 | 0.82 | PPARG (0.44) | PPARAPPARDPPARGTHRBKDM4E | |
| SCHEMBL10039824 | 0.81 | PPARG (0.45) | PPARAPPARDPPARGTHRBKDM4E | |
| SCHEMBL14926751 | 0.80 | THRB (0.62) | PPARAPPARDPPARGTHRBALDH1A1 | |
| SCHEMBL31606932 | 0.80 | THRB (0.62) | PPARAPPARDPPARGTHRBALDH1A1 | |
| SCHEMBL31606928 | 0.80 | THRB (0.62) | PPARAPPARDPPARGTHRBALDH1A1 | |
| SCHEMBL31606936 | 0.80 | THRB (0.62) | PPARAPPARDPPARGTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419620-B2 | Dichroic mixtures | ROLIC LTD C/O ROLIC TECHNOLOGIES LTD (CH) | 2008-09-02 | — | — | US | disclosed |
| EP-1385914-B1 | DICHROIC MIXTURE | ROLIC AG (CH) | 2008-07-23 | — | — | EP | disclosed |
| US-20040164272-A1 | Dichoric mixture | ROLIC AG (CH) | 2004-08-26 | — | — | US | disclosed |
| EP-1256602-A1 | Dichroic mixture | Rolic AG (CH) | 2002-11-13 | — | — | EP | disclosed |