SCHEMBL5047647

SCHEMBL5047647

C=C(C)c1ccccc1.C=Cc1ccccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
GSR P00390 1/20 0.41
TRPA1 O75762 1/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
EGFR P00533 1/20 0.35
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
MAPT P10636 3/20 0.35
MAOB P27338 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974727 0.88 ALDH1A1 (0.48) ALDH1A1GSRKMT2AMEN1LMNA
Allylbenzene SCHEMBL9774331 0.88 ALDH1A1 (0.50) ALDH1A1GSRKMT2AMEN1LMNA
SCHEMBL7622465 0.87 ALDH1A1 (0.41) ALDH1A1KMT2AMEN1LMNAHPGD
Acetic Acid SCHEMBL27301119 0.83 ALDH1A1 (0.72) ALDH1A1GSRTRPA1KMT2AMEN1
Methacrylic Acid SCHEMBL15637610 0.82 ALDH1A1 (0.64) ALDH1A1GSRTRPA1KMT2AMEN1
Toluene SCHEMBL28097461 0.81 ALDH1A1 (0.75) ALDH1A1GSRTRPA1KMT2AMEN1
Styrene SCHEMBL8569768 0.81 ALDH1A1 (0.42) ALDH1A1MAOB
1,1-Dichloroethene SCHEMBL27804488 0.81 ALDH1A1 (0.82) ALDH1A1GSRTRPA1KMT2AMEN1
Ethane SCHEMBL20484119 0.80 ALDH1A1 (0.90) ALDH1A1GSRTRPA1LMNAGRIN2D
SCHEMBL678283 0.80 ALDH1A1 (1.00) ALDH1A1GSRTRPA1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1856299-B1 METHOD OF EXTRACTING SUGAR FROM SUGAR JUICE STICHTING WAGENINGEN RES (NL) 2019-05-22 EP disclosed
US-9243216-B2 Use of a starch base copolymer in conjunction with a maleic polymer and a hydroxypolycarboxylic acid to control hardness under alkaline conditions Ecolab USA, Inc. (US) 2016-01-26 US disclosed
US-20140378364-A1 USE OF A STARCH BASE COPOLYMER IN CONJUNCTION WITH A MALEIC POLYMER AND A HYDROXYPOLYCARBOXYLIC ACID TO CONTROL HARDNESS UNDER ALKALINE CONDITIONS ECOLAB USA INC (US) 2014-12-25 US disclosed
US-8551250-B2 Via adsorbent having unsaturated hydrocarbon groups exposed on its (internal) surface; hydrogen bonding NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2013-10-08 US disclosed
US-20080168982-A1 Method of Extracting Sugar from Sugar Juice STICHTING WAGENINGEN RESEARCH (NL) 2008-07-17 US disclosed
EP-1856299-A2 METHOD OF EXTRACTING SUGAR FROM SUGAR JUICE Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO (NL) 2007-11-21 EP disclosed
WO-2006088360-A2 METHOD OF EXTRACTING SUGAR FROM SUGAR JUICE NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2006-08-24 WO disclosed
US-20030130433-A1 Process for the production of graft polymers INEOS ABS (JERSEY) LIMITED 2003-07-10 US disclosed
US-5180777-A Impact strength at low temperature MONSANTO COMPANY (US) 1993-01-19 US disclosed
EP-0220155-B1 RUBBER-MODIFIED NYLON COMPOSITION Monsanto Company (US) 1991-12-18 EP disclosed
US-4777211-A BLEND OF GRAFT POLYMER, POLYAMIDE, ACID CONTAINING POLYMER-IMPACT STRENGTH MONSANTO COMPANY (US) 1988-10-11 US disclosed
EP-0220155-A1 Rubber-modified nylon composition Monsanto Company (US) 1987-04-29 EP disclosed