SCHEMBL8974727

SCHEMBL8974727

C=C(C)c1ccccc1.C=Cc1cccc(Cl)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
PPP1R15A O75807 1/20 0.37
MELK Q14680 1/20 0.37
PPP1R15B Q5SWA1 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 3/20 0.37
PTGS2 P35354 1/20 0.37
MEN1 O00255 2/20 0.35
GSR P00390 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
TSHR P16473 2/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5047647 0.88 ALDH1A1 (0.64) ALDH1A1NPSR1KMT2ALMNAMEN1
SCHEMBL10697268 0.84 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2L3MBTL1PPP1R15AMELK
SCHEMBL7622465 0.82 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2NPSR1KMT2ALMNA
SCHEMBL40188 0.80 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2L3MBTL1PPP1R15AMELK
SCHEMBL30587141 0.80 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2L3MBTL1PPP1R15AMELK
SCHEMBL5491734 0.79 ALDH1A1 (0.78) ALDH1A1SMN1; SMN2L3MBTL1PPP1R15AMELK
Allylbenzene SCHEMBL9774331 0.78 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A
SCHEMBL4651780 0.76 RAB9A (0.44) ALDH1A1SMN1; SMN2KMT2ALMNAMEN1
SCHEMBL472888 0.76 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2KMT2ALMNAMEN1
SCHEMBL9985258 0.76 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2L3MBTL1PPP1R15AMELK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333879-B1 PROCESS FOR CONTINUOUSLY PRODUCING GRANULAR POLYMER AND PROCESS FOR CONTROLLING PARTICLE SIZE OF SAID POLYMER MITSUBISHI RAYON CO (JP) 1996-04-10 EP disclosed
US-5064938-A Coagulation slurrying MITSUBISHI RAYON CO., LTD. (JP) 1991-11-12 US disclosed
EP-0333879-A1 PROCESS FOR CONTINUOUSLY PRODUCING GRANULAR POLYMER AND PROCESS FOR CONTROLLING PARTICLE SIZE OF SAID POLYMER MITSUBISHI RAYON CO., LTD. (JP) 1989-09-27 EP disclosed