Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781052 | 0.93 | TSHR (0.46) | MAPTLTA4HKMT2AMEN1KDM4E | |
| SCHEMBL3792474 | 0.86 | MAPT (0.49) | MAPTLTA4HKMT2AMEN1KDM4E | |
| SCHEMBL3785690 | 0.86 | MEN1 (0.51) | MAPTLTA4HKMT2AMEN1KDM4E | |
| SCHEMBL29955341 | 0.81 | LTA4H (0.44) | MAPTLTA4HKMT2AMEN1KDM4E | |
| SCHEMBL29956792 | 0.81 | PTGS1 (0.46) | MAPTLTA4HKMT2AMEN1CA12 | |
| SCHEMBL3783765 | 0.81 | LTA4H (0.44) | MAPTLTA4HKMT2AMEN1KDM4E | |
| SCHEMBL4048727 | 0.81 | PTGS1 (0.46) | MAPTLTA4HKMT2AMEN1CA12 | |
| SCHEMBL30167072 | 0.80 | MAPT (0.60) | MAPTLTA4HKMT2AMEN1KDM4E | |
| SCHEMBL11246033 | 0.80 | MAPT (0.60) | MAPTLTA4HKMT2AMEN1KDM4E | |
| SCHEMBL3781210 | 0.79 | RAB9A (0.46) | MAPTLTA4HKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |