Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.74 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.55 |
| ▸ | AXL | P30530 | 2/20 | 0.55 |
| ▸ | PLK4 | O00444 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | ROS1 | P08922 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | FRK | P42685 | 1/20 | 0.55 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.55 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.55 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.55 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.55 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9578379 | 0.87 | IKBKB (0.81) | IKBKBMCL1MKNK2KMT2AKDM4E | |
| SCHEMBL3784526 | 0.86 | IKBKB (0.54) | IKBKBMCL1MAP4K4MKNK2AXL | |
| SCHEMBL3781950 | 0.85 | IKBKB (1.00) | IKBKBMCL1KMT2AKDM4EGFER | |
| SCHEMBL3781881 | 0.84 | MCL1 (0.57) | IKBKBMCL1MAP4K4MKNK2AXL | |
| SCHEMBL3794862 | 0.83 | IKBKB (0.76) | IKBKBMCL1MKNK2KMT2AKDM4E | |
| SCHEMBL28211256 | 0.81 | IKBKB (0.53) | IKBKBMCL1MAP4K4MKNK2AXL | |
| SCHEMBL10713802 | 0.79 | KMT2A (0.84) | IKBKBMCL1KMT2AKDM4EGFER | |
| SCHEMBL29032715 | 0.79 | IKBKB (0.64) | IKBKBKMT2AKDM4EGFERRXFP1 | |
| SCHEMBL1708814 | 0.78 | KMT2A (0.65) | IKBKBMCL1KMT2AKDM4EGFER | |
| SCHEMBL5303404 | 0.78 | IKBKB (0.73) | IKBKBMAP4K4MKNK2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-4686147-A | SILICONE CONTAINING POLYIMIDES INSULATION LAYER | HITACHI, LTD. (JP) | 1987-08-11 | — | — | US | disclosed |