Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.51 |
| ▸ | AXL | P30530 | 2/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ROS1 | P08922 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | FRK | P42685 | 1/20 | 0.51 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.51 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.51 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047743 | 0.86 | IKBKB (0.74) | IKBKBMCL1MKNK2MAP4K4AXL | |
| SCHEMBL3793566 | 0.85 | IKBKB (0.73) | IKBKBMCL1MKNK2MAP4K4PPM1B | |
| SCHEMBL28211256 | 0.84 | IKBKB (0.53) | IKBKBMCL1MKNK2MAP4K4AXL | |
| SCHEMBL3794232 | 0.84 | MCL1 (0.53) | IKBKBMCL1MKNK2MAP4K4AXL | |
| SCHEMBL3781502 | 0.83 | IKBKB (0.55) | IKBKBMCL1MKNK2PARP1PPM1B | |
| SCHEMBL27919911 | 0.81 | MAP4K4 (0.50) | IKBKBMCL1MKNK2MAP4K4AXL | |
| SCHEMBL27724618 | 0.80 | PBRM1 (0.57) | IKBKBMCL1MAOACA1CA2 | |
| SCHEMBL3790353 | 0.79 | MAP4K4 (0.48) | IKBKBMCL1MKNK2MAP4K4AXL | |
| SCHEMBL7409099 | 0.78 | MAPT (0.48) | IKBKBMCL1MEN1CYP3A4CYP2C9 | |
| SCHEMBL28033110 | 0.78 | PPM1B (0.54) | IKBKBMKNK2PPM1BMKNK1PRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | IKBKB 2611/4885MCL1 3100/4885MKNK2 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.