SCHEMBL5048040

SCHEMBL5048040

O=c1ccc2ccc([SH2+])cc2o1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.49
CA9 Q16790 7/20 0.49
CA1 P00915 5/20 0.49
CA3 P07451 4/20 0.49
CA4 P22748 4/20 0.49
CA7 P43166 4/20 0.49
CA14 Q9ULX7 4/20 0.49
CA2 P00918 3/20 0.49
CA5A P35218 3/20 0.49
CA5B Q9Y2D0 2/20 0.49
CA6 P23280 3/20 0.49
MCL1 Q07820 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
LMNA P02545 1/20 0.49
SOST Q9BQB4 1/20 0.49
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 3/20 0.48
MAOB P27338 4/20 0.48
PGR P06401 4/20 0.48
KMT2A Q03164 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5046893 0.82 CA9 (0.52) CA12CA9CA1CA3CA4
SCHEMBL3367847 0.80 CA12 (0.48) CA12CA9CA1CA3CA4
SCHEMBL5045519 0.79 PGR (0.45) CA12CA9CA1CA3CA4
SCHEMBL3370891 0.78 CA12 (0.46) CA12CA9CA1CA3CA4
SCHEMBL3525761 0.78 DRD4 (0.47) CA12CA9CA1CA3CA4
SCHEMBL6869483 0.75 ALDH1A1 (0.49) CA12CA9CA1CA3CA4
SCHEMBL3524219 0.74 ALDH1A1 (0.43) CA12CA9CA1CA3CA4
SCHEMBL3370898 0.74 ALDH1A1 (0.43) CA12CA9CA1CA3CA4
SCHEMBL15842362 0.73 PGR (0.77) CA12CA9CA1CA3CA4
SCHEMBL6879032 0.72 CYP2A6 (0.44) CA12CA9CA1CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-B1 HETEROCYCLE-BEARING ONIUM SALTS WAKO PURE CHEM IND LTD (JP) 2008-12-31 EP disclosed
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed