SCHEMBL5048110

SCHEMBL5048110

CCCC1CN([C@@H](CC)C(=O)NI)C(=O)C1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KAT2A Q92830 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5045298 0.88 CYP1A2 (0.32)
SCHEMBL25220839 0.85 ACE (0.36) KAT2A
SCHEMBL25267433 0.85 ACE (0.36) KAT2A
SCHEMBL433367 0.84 LMNA (0.42) KAT2A
SCHEMBL8236666 0.84 LMNA (0.42) KAT2A
SCHEMBL433366 0.84 LMNA (0.42) KAT2A
SCHEMBL4528165 0.73 LMNA (0.40)
SCHEMBL8236566 0.73 LMNA (0.40)
SCHEMBL4528160 0.73 LMNA (0.40)
SCHEMBL18844857 0.73 BRD4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1993998-A1 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES UCB Pharma, S.A. (BE) 2008-11-26 EP claimed
WO-2007065634-A1 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES UCB PHARMA, S.A. (BE) 2007-06-14 WO claimed