Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.44 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | CDC25C | P30307 | 3/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039914 | 0.92 | CDC25A (0.45) | CDC25ACDC25BCDC25CDUSP3NPC1 | |
| SCHEMBL5043889 | 0.89 | CDC25A (0.43) | CDC25ACDC25BCDC25CDUSP3NPC1 | |
| SCHEMBL5048696 | 0.89 | CDC25A (0.43) | CDC25ACDC25BCDC25CDUSP3NPC1 | |
| SCHEMBL5046954 | 0.89 | CDC25A (0.43) | CDC25ACDC25BCDC25CDUSP3NPC1 | |
| SCHEMBL5043910 | 0.89 | CDC25A (0.45) | CDC25ACDC25BCDC25CDUSP3NPC1 | |
| SCHEMBL5140692 | 0.89 | FAAH (0.46) | CDC25ACDC25BCDC25CDUSP3NPC1 | |
| SCHEMBL5044042 | 0.89 | CDC25A (0.42) | CDC25ACDC25BCDC25CDUSP3NPC1 | |
| SCHEMBL5039564 | 0.88 | FAAH (0.46) | CDC25ACDC25BCDC25CDUSP3ALDH1A1 | |
| SCHEMBL5043836 | 0.88 | CDC25A (0.46) | CDC25ACDC25BCDC25CDUSP3NPC1 | |
| SCHEMBL5044797 | 0.88 | KLKB1 (0.48) | CDC25ACDC25BCDC25CDUSP3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583762-B1 | PYRROLYL-THIAZOLES AND THEIR USE AS CB 1 RECEPTOR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | EP | claimed |