Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823743 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL12317070 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL8264292 | 0.80 | MEN1 (0.55) | ALDH1A1TSHRMEN1THRBHTT | |
| SCHEMBL28912718 | 0.80 | MEN1 (0.55) | ALDH1A1TSHRMEN1THRBHTT | |
| SCHEMBL823708 | 0.80 | CES2 (0.38) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL826533 | 0.80 | CES2 (0.38) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9333522 | 0.80 | MEN1 (0.55) | ALDH1A1TSHRMEN1THRBHTT | |
| SCHEMBL9333495 | 0.80 | MEN1 (0.55) | ALDH1A1TSHRMEN1THRBHTT | |
| SCHEMBL1063406 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL7878546 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TP53TSHRHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798250-B1 | Molecules suitable for binding to a metal layer for covalently immobilizing biomolecules | IMEC INTER UNI MICRO ELECTR (BE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1798250-A2 | Molecules suitable for binding to a metal layer for covalently immobilizing biomolecules | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM vzw (IMEC) (BE) | 2007-06-20 | — | — | EP | disclosed |