Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041476 | 0.88 | MAPT (0.43) | MAPTSMN1; SMN2POLBTHRBNR1H4 | |
| SCHEMBL14095569 | 0.85 | MAPT (0.41) | MAPTSMN1; SMN2POLBTHRBNR1H4 | |
| SCHEMBL5049478 | 0.85 | MAPT (0.37) | MAPTSMN1; SMN2POLBTHRBGPR119 | |
| SCHEMBL5044883 | 0.80 | TLR7 (0.48) | MAPTSMN1; SMN2POLBNR1H4TLR7 | |
| SCHEMBL5045843 | 0.77 | ESR1 (0.55) | MAPTSMN1; SMN2NR1H4GPR119LMNA | |
| SCHEMBL5042502 | 0.76 | TLR7 (0.39) | MAPTSMN1; SMN2POLBNR1H4GPR119 | |
| SCHEMBL5045089 | 0.74 | MEN1 (0.57) | MAPTSMN1; SMN2NR1H4TDP1HSP90AA1 | |
| SCHEMBL5041479 | 0.74 | MAPT (0.38) | MAPTSMN1; SMN2POLBTHRBGPR119 | |
| SCHEMBL14135761 | 0.71 | TLR7 (0.44) | MAPTSMN1; SMN2POLBTHRBGPR119 | |
| SCHEMBL14095573 | 0.69 | MAPT (0.49) | MAPTSMN1; SMN2NR1H4TDP1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414138-B2 | Benzoxazole and benzodiazole UV-A sunscreens | DSM IP ASSETS B.V. (NL) | 2008-08-19 | — | — | US | disclosed |
| US-20050260144-A1 | Benzoxazole and benzodiazole uv-a sunscreens | DSM IP ASSETS B.V. (NL) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050260144-A1 | Benzoxazole and benzodiazole uv-a sunscreens | SUN2, CYP27B1, ERCC4 | MAPT 543/4885SMN1; SMN2 3995/4885POLB 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.