Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.65 |
| ▸ | CNR2 | P34972 | 17/20 | 0.45 |
| ▸ | CNR1 | P21554 | 16/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050245 | 0.93 | HSP90AB1 (0.63) | HSP90AB1CNR2CNR1 | |
| SCHEMBL5051707 | 0.88 | HSP90AB1 (0.69) | HSP90AB1CNR2CNR1SLC5A1SLC5A2 | |
| SCHEMBL9202392 | 0.84 | HSP90AB1 (0.69) | HSP90AB1 | |
| SCHEMBL2977953 | 0.82 | HSP90AB1 (0.76) | HSP90AB1 | |
| SCHEMBL27088422 | 0.80 | PLA2G2A (0.58) | HSP90AB1CNR2CNR1 | |
| SCHEMBL8151711 | 0.80 | HSP90AB1 (0.92) | HSP90AB1 | |
| SCHEMBL478058 | 0.80 | HSP90AB1 (1.00) | HSP90AB1 | |
| SCHEMBL1592618 | 0.79 | HSP90AB1 (0.61) | HSP90AB1 | |
| SCHEMBL28588436 | 0.79 | KMT2A (0.55) | — | |
| SCHEMBL14558932 | 0.78 | HSP90AB1 (0.53) | HSP90AB1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| EP-1940767-A2 | PPARACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007030567-A2 | PPARACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007030567-A2 | PPARACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2007-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PPARG, PPARA, PPARD | HSP90AB1 349/4885CNR2 288/4885CNR1 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.