SCHEMBL478058

SCHEMBL478058

COC(=O)Cc1cc(O)cc(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 1.00
ALDH1A1 P00352 4/20 0.53
GAA P10253 2/20 0.53
GFER P55789 1/20 0.53
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
SLC7A5 Q01650 1/20 0.42
TSHR P16473 2/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
ACHE P22303 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
EGFR P00533 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8151711 0.96 HSP90AB1 (0.92) HSP90AB1ALDH1A1GAAGFERCYP4F2
SCHEMBL2973152 0.88 HSP90AB1 (0.79) HSP90AB1ALDH1A1GAAGFERCYP4F2
SCHEMBL14626268 0.88 HSP90AB1 (0.79) HSP90AB1ALDH1A1GAAGFERCYP4F2
SCHEMBL2984242 0.87 HSP90AB1 (0.76) HSP90AB1ALDH1A1GAAGFERCYP4F2
SCHEMBL27725733 0.87 HSP90AB1 (0.76) HSP90AB1ALDH1A1GAAGFERCYP4F2
SCHEMBL2977953 0.87 HSP90AB1 (0.76) HSP90AB1ALDH1A1GAAGFERCYP4F2
SCHEMBL350066 0.87 HSP90AB1 (0.76) HSP90AB1ALDH1A1GAAGFERCYP4F2
SCHEMBL21891794 0.86 HSP90AB1 (0.75) HSP90AB1ALDH1A1GAAGFERCYP4F2
SCHEMBL9202392 0.82 HSP90AB1 (0.69) HSP90AB1ALDH1A1GAAGFERCYP4F2
SCHEMBL5051707 0.82 HSP90AB1 (0.69) HSP90AB1ALDH1A1GAAGFERCYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425192-B Powder material special for PS-PVD, preparation method and application 北京伽瓦新材料科技有限公司 2023-11-14 CN claimed
CN-116425192-A Powder material special for PS-PVD, preparation method and application 北京伽瓦新材料科技有限公司 2023-07-14 CN claimed
EP-4320138-B1 PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES BACHEM AG (CH) 2026-04-01 EP disclosed
US-20250282813-A1 PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES BACHEM HOLDING AG (CH) 2025-09-11 US disclosed
US-11964956-B2 Cannabinergic compounds and uses thereof NORTHEASTERN UNIVERSITY (US) 2024-04-23 US disclosed
EP-4320138-A1 PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES Bachem Holding AG (CH) 2024-02-14 EP disclosed
US-20240025858-A1 CANNABINOID DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHOD OF PREPARATION THEREOF JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2024-01-25 US disclosed
US-20240025858-A1 CANNABINOID DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHOD OF PREPARATION THEREOF JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2024-01-25 US disclosed
CN-116425192-B Powder material special for PS-PVD, preparation method and application 北京伽瓦新材料科技有限公司 2023-11-14 CN disclosed
EP-4262980-A1 CANNABINOID DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHOD OF PREPARATION THEREOF GW Research Limited (GB) 2023-10-25 EP disclosed
CN-116685569-A Cannabinoid derivatives as pharmaceutically active compounds and process for their preparation 吉伟研究有限公司 2023-09-01 CN disclosed
EP-1337527-A1 INDOLYLMALEIMIDE DERIVATIVES AS PROTEIN KINASE C INHIBITORS Novartis AG (CH) 2003-08-27 EP disclosed
US-6596772-B1 Relates to trifluoromethyl sulfonyl and trifluoromethyl sulfonamido compounds and the physiologically acceptable salts and the prodrugs thereof. These compounds are expected to modulate the activity of protein tyrosine enzymes which are SUGEN, INC. 2003-07-22 US disclosed
US-20030069424-A1 Indolylmaleimide derivatives NOVARTIS AG (CH) 2003-04-10 US disclosed
EP-1268525-A2 MACROCYCLIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS COMPRISING N-CYCLIC P2 MOIETIES SCHERING CORPORATION (US) 2003-01-02 EP disclosed
US-20020107181-A1 Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising N-cyclic P2 moieties SCHERING CORPORATION 2002-08-08 US disclosed
EP-1212296-A1 PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS Sugen, Inc. (US) 2002-06-12 EP disclosed
WO-2002038561-A1 INDOLYLMALEIMIDE DERIVATIVES AS PROTEIN KINASE C INHIBITORS NOVARTIS AG (CH) 2002-05-16 WO disclosed
WO-2001077113-A2 MACROCYCLIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS COMPRISING N-CYCLIC P2 MOIETIES SCHERING CORPORATION (US) 2001-10-18 WO disclosed
WO-2001016097-A1 PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS SUGEN, INC. (US) 2001-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11964956-B2 Cannabinergic compounds and uses thereof CNR2, CNR1, GPR18 HSP90AB1 701/4885ALDH1A1 2734/4885GAA 796/4885
US-20030069424-A1 Indolylmaleimide derivatives NFATC1, INMT, IDO1 HSP90AB1 3709/4885ALDH1A1 1752/4885GAA 3119/4885
US-20240025858-A1 CANNABINOID DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHOD OF PREPARATION THEREOF CNR1, CNR2, FAAH HSP90AB1 3897/4885ALDH1A1 3920/4885GAA 1878/4885
US-20020107181-A1 Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising N-cyclic P2 moieties HPN, TMPRSS15, HAVCR2 HSP90AB1 2862/4885ALDH1A1 2837/4885GAA 1668/4885
US-20250282813-A1 PSEUDO SOLID PHASE PROTECTING GROUP AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND OLIGONUCLEOTIDE CONJUGATES POLR2H, POLR2E, SUB1 HSP90AB1 3834/4885ALDH1A1 2910/4885GAA 3974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.