Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536243 | 0.85 | SLC1A1 (0.58) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| SCHEMBL2018995 | 0.85 | SLC1A1 (0.58) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| SCHEMBL151676 | 0.85 | SLC1A1 (0.58) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| Hydrochloric Acid SCHEMBL23851398 | 0.83 | SLC1A1 (0.56) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| Hydrochloric Acid SCHEMBL933300 | 0.83 | SLC1A1 (0.56) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| SCHEMBL2238405 | 0.83 | SLC1A1 (0.56) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| Hydrochloric Acid SCHEMBL6506409 | 0.83 | SLC1A1 (0.56) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| SCHEMBL14456726 | 0.82 | MGAM (0.50) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| Hydrochloric Acid SCHEMBL5623486 | 0.81 | MGAM (0.48) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| Hydrochloric Acid SCHEMBL5622539 | 0.81 | MGAM (0.48) | SLC1A1SLC7A5GRIK1GRIK2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045507-B2 | Coumarin-based amino acids for use in enzyme activity and substrate specificity assays | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-06-02 | — | — | US | disclosed |
| EP-1946102-A1 | COUMARIN-BASED AMINO ACIDS FOR USE IN ENZYME ACTIVITY AND SUBSTRATE SPECIFICITY ASSAYS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-07-23 | — | — | EP | disclosed |
| US-20070031892-A1 | Novel coumarin-based amino acids for use in enzyme activity and substrate specificity assays | USC | 2007-02-08 | — | — | US | disclosed |
| WO-2007014326-A1 | COUMARIN-BASED AMINO ACIDS FOR USE IN ENZYME ACTIVITY AND SUBSTRATE SPECIFICITY ASSAYS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-02-01 | — | — | WO | disclosed |