Sugi Predict

Sugi Predict / Compounds / SCHEMBL536243

SCHEMBL536243

SCHEMBL536243

COC(=O)CC(N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SLC1A1 P43005 4/20 0.58
▸ SLC7A5 Q01650 2/20 0.50
▸ GRIK1 P39086 9/20 0.48
▸ GRIK2 Q13002 5/20 0.48
▸ GRM1 Q13255 1/20 0.46
▸ GRM2 Q14416 1/20 0.46
▸ GRIA4 P48058 3/20 0.45
▸ GRIK3 Q13003 3/20 0.45
▸ GRIK5 Q16478 3/20 0.45
▸ SLC1A3 P43003 4/20 0.45
▸ SLC1A2 P43004 4/20 0.45
▸ GRIA2 P42262 2/20 0.44
▸ GRIA1 P42261 1/20 0.44
▸ GFPT1 Q06210 1/20 0.43
▸ PTGS1 P23219 1/20 0.42
▸ SLC7A11 Q9UPY5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL151676 1.00 SLC1A1 (0.58) SLC1A1SLC7A5GRIK1GRIK2GRM1
SCHEMBL2018995 1.00 SLC1A1 (0.58) SLC1A1SLC7A5GRIK1GRIK2GRM1
Hydrochloric Acid SCHEMBL6506409 0.98 SLC1A1 (0.56) SLC1A1SLC7A5GRIK1GRIK2GRM1
SCHEMBL2238405 0.98 SLC1A1 (0.56) SLC1A1SLC7A5GRIK1GRIK2GRM1
Hydrochloric Acid SCHEMBL933300 0.98 SLC1A1 (0.56) SLC1A1SLC7A5GRIK1GRIK2GRM1
Hydrochloric Acid SCHEMBL23851398 0.98 SLC1A1 (0.56) SLC1A1SLC7A5GRIK1GRIK2GRM1
Hydrochloric Acid SCHEMBL25212271 0.96 SLC1A1 (0.55) SLC1A1SLC7A5GRIK1GRIK2GRM1
SCHEMBL9449386 0.86 SLC1A1 (0.54) SLC1A1SLC7A5GRIK1GRIK2GRM1
SCHEMBL7359265 0.86 SLC1A1 (0.54) SLC1A1SLC7A5GRIK1GRIK2GRM1
SCHEMBL5050477 0.85 SLC1A1 (0.53) SLC1A1SLC7A5GRIK1GRIK2GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11229621-B2 Pharmaceutical compositions of dimethyl fumarate ARBOR PHARMACEUTICALS, LLC (US) 2022-01-25 — — US claimed
US-20200155496-A1 Pharmaceutical Compositions of Dimethyl Fumarate HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2020-05-21 — — US claimed
CN-105254573-B A kind of preparation method of Taltirelin and its intermediate 重庆莱美隆宇药业有限公司 2018-01-23 — — CN claimed
CN-106117548-A A kind of amino acidic group cluster peptide and preparation method thereof 中国科学院长春应用化学研究所 2016-11-16 — — CN claimed
CN-105613529-A Insecticide for aedes albopictus YANTAI MILUOKA CHEMICAL TECH CO LTD 2016-06-01 — — CN claimed
WO-2014160633-A1 PHARMACEUTICAL COMPOSITIONS OF DIMETHYL FUMARATE XENOPORT, INC. (US) 2014-10-02 — — WO claimed
US-20140284245-A1 PHARMACEUTICAL COMPOSITIONS OF DIMETHYL FUMARATE XENOPORT, INC. (US) 2014-09-25 — — US claimed
CN-115298194-B VIPR2 antagonistic peptide 一丸自然美健有限公司 2026-05-12 — — CN disclosed
US-12440468-B2 Pharmaceutical compositions of dimethyl fumarate ARBOR PHARMACEUTICALS, LLC (US) 2025-10-14 — — US disclosed
US-20250186540-A1 VIPR2 ANTAGONIST PEPTIDE FOR SUPPRESSING CANCER METASTASIS ICHIMARU PHARCOS CO., LTD. (JP) 2025-06-12 — — US disclosed
US-20250136620-A1 BTK DEGRADER NEWAVE PHARMACEUTICAL INC. 2025-05-01 — — US disclosed
EP-4541891-A1 NOVEL LRP1-BINDING PEPTIDE Ichimaru Pharcos Co., Ltd. (JP) 2025-04-23 — — EP disclosed
CN-119630790-A Novel LRP1 binding peptides 一丸自然美健有限公司 2025-03-14 — — CN disclosed
US-20070142415-A1 Heteroarylpyrrolopyridinones active as kinase inhibitors PHARMACIA ITALIA S.P.A. (IT) 2007-06-21 — — US disclosed
EP-1313716-B1 OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS LILLY CO ELI (US) 2007-05-02 — — EP disclosed
WO-2005040127-A1 NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME LG LIFE SCIENCES LTD. (KR) 2005-05-06 — — WO disclosed
EP-0799221-B1 QUINAZOLINES AS INHIBITORS OF ENDOTHELIN CONVERTING ENZYME WARNER LAMBERT CO (US) 2002-10-30 — — EP disclosed
CN-1077110-C 13-substituted milbemycin 5-oxime derivatives their preparation and their use against insects and other pests SANKYO CO (JP) 2002-01-02 — — CN disclosed
CN-1153177-A 13-substituted milbemycin 5-oxime derivatives their preparation and their use against insects and other pests SANKYO CO (JP) 1997-07-02 — — CN disclosed
US-5338760-A Urea derivatives, their preparation and medicinal products containing them RHONE-POULENC RORER S.A. (FR) 1994-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11229621-B2 Pharmaceutical compositions of dimethyl fumarate FH, SDHB, SDHA SLC1A1 3100/4885SLC7A5 598/4885GRIK1 4416/4885
US-20200155496-A1 Pharmaceutical Compositions of Dimethyl Fumarate FH, SDHB, SDHA SLC1A1 3100/4885SLC7A5 598/4885GRIK1 4416/4885
US-12440468-B2 Pharmaceutical compositions of dimethyl fumarate FH, SDHB, SDHA SLC1A1 3100/4885SLC7A5 598/4885GRIK1 4416/4885
US-20070142415-A1 Heteroarylpyrrolopyridinones active as kinase inhibitors MAP3K1, MAP3K19, MAP3K3 SLC1A1 3990/4885SLC7A5 3626/4885GRIK1 522/4885
US-20140284245-A1 PHARMACEUTICAL COMPOSITIONS OF DIMETHYL FUMARATE FH, SDHB, SDHA SLC1A1 3100/4885SLC7A5 598/4885GRIK1 4416/4885
US-20250136620-A1 BTK DEGRADER BTK, CBL, LYN SLC1A1 4856/4885SLC7A5 4799/4885GRIK1 3379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.