Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053900 | 0.87 | SERPINE1 (0.40) | SERPINE1TSHRALDH1A1LMNAESR1 | |
| SCHEMBL5050530 | 0.86 | CES2 (0.41) | SERPINE1TSHRALDH1A1LMNATP53 | |
| SCHEMBL5049251 | 0.84 | SERPINE1 (0.50) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL5053888 | 0.81 | RAB9A (0.44) | SERPINE1TSHRALDH1A1LMNARARA | |
| SCHEMBL823817 | 0.81 | ESR1 (0.44) | SERPINE1ESR1CYP3A4 | |
| SCHEMBL825582 | 0.81 | ESR1 (0.44) | SERPINE1ESR1CYP3A4 | |
| SCHEMBL3625514 | 0.81 | ESR1 (0.44) | SERPINE1ESR1CYP3A4 | |
| SCHEMBL825719 | 0.80 | RARB (0.37) | SERPINE1ALDH1A1RARARARB | |
| SCHEMBL826523 | 0.77 | RARB (0.37) | ALDH1A1RARARARB | |
| SCHEMBL826549 | 0.77 | SERPINE1 (0.44) | SERPINE1ALDH1A1ESR1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798250-B1 | Molecules suitable for binding to a metal layer for covalently immobilizing biomolecules | IMEC INTER UNI MICRO ELECTR (BE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1798250-A2 | Molecules suitable for binding to a metal layer for covalently immobilizing biomolecules | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM vzw (IMEC) (BE) | 2007-06-20 | — | — | EP | disclosed |