Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050582 | 1.00 | MAPT (0.48) | MAPTNPC1RAB9AGAATRPA1 | |
| SCHEMBL28557804 | 1.00 | MAPT (0.48) | MAPTNPC1RAB9AGAATRPA1 | |
| SCHEMBL29966795 | 1.00 | MAPT (0.48) | MAPTNPC1RAB9AGAATRPA1 | |
| SCHEMBL9734139 | 0.87 | MAPT (0.48) | MAPTNPC1RAB9AGAATRPA1 | |
| SCHEMBL9734131 | 0.87 | MAPT (0.48) | MAPTNPC1RAB9AGAATRPA1 | |
| SCHEMBL31542595 | 0.87 | TRPA1 (0.43) | MAPTNPC1RAB9ATRPA1ALDH1A1 | |
| SCHEMBL9451419 | 0.87 | TRPA1 (0.43) | MAPTNPC1RAB9ATRPA1ALDH1A1 | |
| SCHEMBL9451414 | 0.87 | TRPA1 (0.43) | MAPTNPC1RAB9ATRPA1ALDH1A1 | |
| SCHEMBL9668754 | 0.86 | MAPT (0.47) | MAPTNPC1RAB9AGAATRPA1 | |
| SCHEMBL9733978 | 0.86 | MAPT (0.47) | MAPTNPC1RAB9AGAATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110317122-B | Method for converting E-type epoxiconazole intermediate into Z-type epoxiconazole intermediate | 东南大学 | 2021-11-02 | — | — | CN | claimed |
| CN-112661599-A | Synthesis method of (Z) -3-halogenated-2- (4-fluorophenyl) -1- (2-chlorphenyl) propylene | 浙江工业大学 | 2021-04-16 | — | — | CN | claimed |
| CN-101208322-A | Improved synthesis of substituted 1-halomethyl-2-phenyl-1-phenyl oxirane | MAKHTESHIM CHEM WORKS LTD (IL) | 2008-06-25 | — | — | CN | claimed |
| EP-1899312-A2 | IMPROVED SYNTHESIS OF SUBSTITUTED 1-HALOMETHYL-2-PHENYL-1-PHENYL OXIRANE | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 2008-03-19 | — | — | EP | claimed |
| WO-2007000759-A2 | SYNTHESIS OF SUBSTITUTED l-HALOMETHYL-2-PHENYL-l-PHENYL OXIRANE | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2007-01-04 | — | — | WO | claimed |
| CN-119591472-A | Synthesis method and application of epoxiconazole intermediate | 江西华士药业有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-112661599-B | Synthesis method of (Z) -3-halogenated-2- (4-fluorophenyl) -1- (2-chlorphenyl) propylene | 浙江工业大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-110317122-B | Method for converting E-type epoxiconazole intermediate into Z-type epoxiconazole intermediate | 东南大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-110317122-B | Method for converting E-type epoxiconazole intermediate into Z-type epoxiconazole intermediate | 东南大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-112661599-A | Synthesis method of (Z) -3-halogenated-2- (4-fluorophenyl) -1- (2-chlorphenyl) propylene | 浙江工业大学 | 2021-04-16 | — | — | CN | disclosed |
| CN-108530263-A | A kind of separation and concentration Z-type and the chloro- 2- of E types 3-（4- fluorophenyls）-1-（2- chlorphenyls）The method of propylene | 东南大学 | 2018-09-14 | — | — | CN | disclosed |
| CN-101208322-A | Improved synthesis of substituted 1-halomethyl-2-phenyl-1-phenyl oxirane | MAKHTESHIM CHEM WORKS LTD (IL) | 2008-06-25 | — | — | CN | disclosed |
| EP-1899312-A2 | IMPROVED SYNTHESIS OF SUBSTITUTED 1-HALOMETHYL-2-PHENYL-1-PHENYL OXIRANE | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000759-A2 | SYNTHESIS OF SUBSTITUTED l-HALOMETHYL-2-PHENYL-l-PHENYL OXIRANE | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2007-01-04 | — | — | WO | disclosed |
| US-5268517-A | Dehydrating an aromatic chlorohydrin | BASF AKTIENGESELLSCHAFT (DE) | 1993-12-07 | — | — | US | disclosed |
| EP-0409049-B1 | METHOD FOR THE STEREOSELECTIVE PRODUCTION OF Z-1,2-DIARYL-ALKYL-CHLORIDES AND THEIR CONVERSION TO AZOLYLMETHYLOXIRANES AS WELL AS INTERMEDIATES | BASF Aktiengesellschaft (DE) | 1993-03-10 | — | — | EP | disclosed |
| EP-0409049-A2 | Method for the stereoselective production of Z-1,2-diaryl-alkyl-chlorides and their conversion to azolylmethyloxiranes as well as intermediates | BASF Aktiengesellschaft (DE) | 1991-01-23 | — | — | EP | disclosed |