Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668754 | 1.00 | MAPT (0.47) | MAPTNPC1RAB9ATRPA1F2R | |
| SCHEMBL9733987 | 1.00 | MAPT (0.47) | MAPTNPC1RAB9ATRPA1F2R | |
| SCHEMBL29966926 | 1.00 | MAPT (0.47) | MAPTNPC1RAB9ATRPA1F2R | |
| SCHEMBL9669401 | 0.87 | TRPA1 (0.44) | MAPTNPC1RAB9ATRPA1PTPN1 | |
| SCHEMBL9669407 | 0.87 | TRPA1 (0.44) | MAPTNPC1RAB9ATRPA1PTPN1 | |
| SCHEMBL5050582 | 0.86 | MAPT (0.48) | MAPTNPC1RAB9ATRPA1F2R | |
| SCHEMBL5050581 | 0.86 | MAPT (0.48) | MAPTNPC1RAB9ATRPA1F2R | |
| SCHEMBL29966795 | 0.86 | MAPT (0.48) | MAPTNPC1RAB9ATRPA1F2R | |
| SCHEMBL28557804 | 0.86 | MAPT (0.48) | MAPTNPC1RAB9ATRPA1F2R | |
| SCHEMBL9734139 | 0.86 | MAPT (0.48) | MAPTNPC1RAB9ATRPA1F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098917-A | And process for killing fungi | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |
| US-5028618-A | Imidazole oxirane compounds | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0352675-A2 | Substituted imidazolylmethyloxiranes and substituted imidazolylpropenes, their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1990-01-31 | — | — | EP | disclosed |