Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.72 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397373 | 0.89 | MYC (0.74) | MYCALDH1A1HPGDFABP4KDM4E | |
| SCHEMBL9512847 | 0.84 | MYC (1.00) | MYCALDH1A1HPGDFABP4KDM4E | |
| SCHEMBL4138458 | 0.84 | MYC (0.72) | MYCPDK2ALDH1A1HPGDCA1 | |
| SCHEMBL29087835 | 0.83 | MYC (0.50) | MYCALDH1A1SMN1; SMN2BRPF1HPGD | |
| SCHEMBL11104104 | 0.81 | MYC (0.68) | MYCALDH1A1SMN1; SMN2HPGDCA1 | |
| SCHEMBL3908254 | 0.80 | MYC (0.53) | MYCPDK2ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL978600 | 0.80 | KDM4C (0.50) | MYCPDK2ALDH1A1SMN1; SMN2BRD4 | |
| SCHEMBL26446322 | 0.79 | ALDH1A1 (0.51) | MYCALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL28566405 | 0.78 | MYC (0.82) | MYCALDH1A1HPGDFABP4KDM4E | |
| SCHEMBL17292717 | 0.78 | KEAP1 (0.53) | MYCPDK2ALDH1A1HPGDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885669-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | Promerus LLC (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006128097-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | PROMERUS LLC (US) | 2006-11-30 | — | — | WO | disclosed |