Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775183 | 0.93 | MEN1 (0.53) | MEN1NPC1KMT2AL3MBTL1FDPS | |
| SCHEMBL881495 | 0.88 | MEN1 (0.45) | MEN1NPC1KMT2AL3MBTL1FDPS | |
| SCHEMBL16973543 | 0.85 | PPARA (0.50) | MEN1NPC1KMT2AL3MBTL1FDPS | |
| SCHEMBL11864849 | 0.80 | TACR2 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL13185202 | 0.80 | BIRC5 (0.46) | MEN1NPC1KMT2AL3MBTL1FDPS | |
| SCHEMBL13062645 | 0.80 | FDPS (0.42) | MEN1NPC1KMT2AL3MBTL1FDPS | |
| SCHEMBL1766003 | 0.79 | PPARA (0.54) | MEN1NPC1KMT2AL3MBTL1FDPS | |
| SCHEMBL8788295 | 0.79 | FDPS (0.51) | MEN1NPC1KMT2AL3MBTL1FDPS | |
| SCHEMBL3401269 | 0.79 | CSNK2A1 (0.51) | MEN1NPC1KMT2AL3MBTL1FDPS | |
| SCHEMBL1057005 | 0.79 | NPC1 (0.47) | MEN1NPC1KMT2AL3MBTL1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035209-A2 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY | METHYLGENE INC. (CA) | 2008-03-27 | — | — | WO | disclosed |