Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031578 | 0.93 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2HCRTR1HDAC3HDAC1 | |
| SCHEMBL346020 | 0.93 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2HCRTR1HDAC3HDAC1 | |
| SCHEMBL900949 | 0.88 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2HDAC3HDAC6KMT2A | |
| SCHEMBL321300 | 0.83 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2HDAC3HDAC6KMT2A | |
| SCHEMBL182506 | 0.81 | — | — | |
| SCHEMBL8741061 | 0.80 | SMN1; SMN2 (0.32) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC4 | |
| SCHEMBL2283058 | 0.80 | HPGD (0.46) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1HPGD | |
| SCHEMBL9136880 | 0.79 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC4 | |
| SCHEMBL29361373 | 0.79 | HPGD (0.37) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC4 | |
| SCHEMBL44111 | 0.79 | HPGD (0.37) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005086775-A2 | LUMEN-EXPOSED MOLECULES AND METHODS FOR TARGETED DELIVERY | UTAH VENTURES II, L.P. (US) | 2005-09-22 | — | — | WO | claimed |
| US-20040146516-A1 | Lumen-exposed molecules and methods for targeted delivery | UTAH VENTURES II L.P. | 2004-07-29 | — | — | US | claimed |
| EP-4683674-A1 | COMPOSITIONS AND METHODS FOR DELIVERING ANTIBODY OLIGONUCLEOTIDE CONJUGATES FOR EXON SKIPPING | Yale University (US) | 2026-01-28 | — | — | EP | disclosed |
| EP-4655007-A1 | ANTIBODY OLIGONUCLEOTIDE CONJUGATES | Yale University (US) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024197302-A1 | COMPOSITIONS AND METHODS FOR DELIVERING ANTIBODY OLIGONUCLEOTIDE CONJUGATES FOR EXON SKIPPING | YALE UNIVERSITY (US) | 2024-09-26 | — | — | WO | disclosed |
| WO-2024158824-A1 | ANTIBODY OLIGONUCLEOTIDE CONJUGATES | YALE UNIVERSITY (US) | 2024-08-02 | — | — | WO | disclosed |
| US-20230248852-A1 | Nanoparticle Photoacoustic Imaging Agents | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2023-08-10 | — | — | US | disclosed |
| US-11548953-B2 | Receptor tyrosine kinase-like orphan receptor 1 (ROR1) single chain Fv antibody fragment conjugates and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-01-10 | — | — | US | disclosed |
| US-10905775-B2 | Particulate constructs for release of active agents | CELATOR PHARMACEUTICALS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20200054772-A1 | Nanoparticle Photoacoustic Imaging Agents | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-02-20 | — | — | US | disclosed |
| US-20180221509-A1 | PARTICULATE CONSTRUCTS FOR RELEASE OF ACTIVE AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-08-09 | — | — | US | disclosed |
| US-20170042823-A1 | CO-ENCAPSULATION OF ANTIMICROBIALS AND ADJUVANTS IN NANOCARRIERS | UNIV PRINCETON (US) | 2017-02-16 | — | — | US | disclosed |
| US-20160082134-A1 | Nanoparticle Photoacoustic Imaging Agents | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-03-24 | — | — | US | disclosed |
| US-20130336915-A1 | PARTICULATE CONSTRUCTS FOR RELEASE OF ACTIVE AGENTS | Jazz Pharmaceuticals Therapeutics, Inc. | 2013-12-19 | — | — | US | disclosed |
| US-20130337078-A1 | PARTICULATE CONSTRUCTS FOR RELEASE OF ACTIVE AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-12-19 | — | — | US | disclosed |
| US-20080299205-A1 | Particulate Constructs For Release of Active Agents | CELATOR PHARMACEUTICALS, INC. | 2008-12-04 | — | — | US | disclosed |