Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321300 | 0.93 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL5051008 | 0.88 | ALDH1A1 (0.34) | SMN1; SMN2HDAC3HDAC6KMT2AALDH1A1 | |
| SCHEMBL16491630 | 0.88 | HDAC6 (0.35) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL15493502 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL346020 | 0.83 | ALDH1A1 (0.33) | SMN1; SMN2HDAC3HDAC6KMT2AALDH1A1 | |
| SCHEMBL30031578 | 0.83 | ALDH1A1 (0.33) | SMN1; SMN2HDAC3HDAC6KMT2AALDH1A1 | |
| SCHEMBL15080491 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9ATP53HDAC3 | |
| SCHEMBL2283058 | 0.80 | HPGD (0.46) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9136880 | 0.79 | ALDH1A1 (0.34) | SMN1; SMN2NPC1HDAC3HDAC6KMT2A | |
| SCHEMBL179849 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ATP53HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100209352-A1 | SYNTHESIS AND CONJUGATION OF IRON OXIDE NANOPARTICLES TO ANTIBODIES FOR TARGETING SPECIFIC CELLS USING FLUORESCENCE AND MR IMAGING TECHNIQUES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) | 2010-08-19 | — | — | US | claimed |
| US-20070059775-A1 | Synthesis and conjugation of iron oxide nanoparticles to antibodies for targeting specific cells using fluorescence and MR imaging techniques | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-03-15 | — | — | US | claimed |
| US-20060223156-A1 | Controlled dissolution crosslinked protein in crystals | ALTHEA TECHNOLOGIES, INC. | 2006-10-05 | — | — | US | claimed |
| EP-0701448-B1 | AMPLIFICATION OF THE VITAMIN B 12 UPTAKE SYSTEM USING POLYMERS | BIOTECH AUSTRALIA PTY LTD (AU) | 2002-08-14 | — | — | EP | claimed |
| US-20230355730-A1 | METHODS FOR TREATING AUTOIMMUNE DISEASE USING BIOCOMPATIBLE BIOABSORBABLE NANOSPHERES | UTI LIMITED PARTNERSHIP (CA) | 2023-11-09 | — | — | US | disclosed |
| US-20230248852-A1 | Nanoparticle Photoacoustic Imaging Agents | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2023-08-10 | — | — | US | disclosed |
| US-20210145949-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF AUTOIMMUNE CONDITIONS | MOORE, ANNA | 2021-05-20 | — | — | US | disclosed |
| US-11000596-B2 | Compositions and methods for the prevention and treatment of cancer | UTI Limited Parttiership (CA) | 2021-05-11 | — | — | US | disclosed |
| US-10905775-B2 | Particulate constructs for release of active agents | CELATOR PHARMACEUTICALS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| EP-2842570-B1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF AUTOIMMUNE CONDITIONS | UTI LP (CA) | 2020-05-06 | — | — | EP | disclosed |
| US-20200054772-A1 | Nanoparticle Photoacoustic Imaging Agents | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-02-20 | — | — | US | disclosed |
| US-20190134171-A1 | METHODS FOR TREATING AUTOIMMUNE DISEASE USING BIOCOMPATIBLE BIOABSORBABLE NANOSPHERES | UTI LIMITED PARTNERSHIP | 2019-05-09 | — | — | US | disclosed |
| US-20090081184-A1 | NON-PANCREATIC PROTEASES FOR CONTROLLING PLASMA CHOLECYSTOKININ (CCK) CONCENTRATION AND FOR TREATING PAIN | ALTUS PHARMACEUTICALS INC. (US) | 2009-03-26 | — | — | US | disclosed |
| WO-2008156638-A2 | METHOD OF TREATING DISORDERS THAT WOULD BENEFIT FROM INCREASED LEVELS OF BILIRUBIN IN A SUBJECT | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2008-12-24 | — | — | WO | disclosed |
| US-20080299205-A1 | Particulate Constructs For Release of Active Agents | CELATOR PHARMACEUTICALS, INC. | 2008-12-04 | — | — | US | disclosed |
| EP-1985699-A1 | Controlled dissolution crosslinked protein crystals | Altus Pharmaceuticals Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2008109852-A2 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF AUTOIMMUNE CONDITIONS | UTI LIMITED PARTNERSHIP (CA) | 2008-09-12 | — | — | WO | disclosed |
| US-20070059775-A1 | Synthesis and conjugation of iron oxide nanoparticles to antibodies for targeting specific cells using fluorescence and MR imaging techniques | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-03-15 | — | — | US | disclosed |
| US-6670322-B2 | Covalently bonding a drug such as captopril to a biopolymeric delivery vehicle such as amino-dextrans, and conjugating the prodrug to a botulinum neurotoxin heavy chain; possible treatment for biological warfare exposure of the toxin | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-12-30 | — | — | US | disclosed |
| US-20030147921-A1 | Method of targeting pharmaceuticals to motor neurons | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-08-07 | — | — | US | disclosed |