Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453532 | 0.87 | PLAU (0.50) | KDM4EHPGDESR1ESR2CES2 | |
| SCHEMBL27443700 | 0.84 | ESR1 (0.78) | KDM4EHPGDESR1ESR2CES2 | |
| SCHEMBL873994 | 0.82 | HPGD (0.72) | KDM4EHPGDCES2CES1SMN1; SMN2 | |
| SCHEMBL28584481 | 0.82 | MEN1 (0.54) | KDM4EHPGDESR1ESR2CES2 | |
| SCHEMBL28856499 | 0.81 | ALDH1A1 (0.53) | KDM4EHPGDESR1ESR2MEN1 | |
| SCHEMBL2470632 | 0.81 | PLAU (0.75) | KDM4EESR1ESR2CES2CES1 | |
| SCHEMBL11848661 | 0.81 | ESR1 (0.59) | KDM4EHPGDESR1ESR2CES2 | |
| SCHEMBL133668 | 0.78 | KDM4E (0.67) | KDM4EHPGDCES2CES1SMN1; SMN2 | |
| SCHEMBL15821561 | 0.78 | CES2 (0.59) | KDM4EHPGDESR1ESR2CES2 | |
| SCHEMBL3302319 | 0.78 | CES2 (0.59) | KDM4EHPGDESR1ESR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096117-A1 | Bisazo compound, 2-hydroxy-3-phenylcarbamoyl naphthalene compound and method manufacturing bisazo compound | RICOH COMPANY, LTD. | 2008-04-24 | — | — | US | claimed |
| US-7897309-B2 | Bisazo compound, 2-hydroxy-3-phenylcarbamoyl naphthalene compound and method manufacturing bisazo compound | RICOH COMPANY, LTD. (JP) | 2011-03-01 | — | — | US | disclosed |
| US-7897309-B2 | Bisazo compound, 2-hydroxy-3-phenylcarbamoyl naphthalene compound and method manufacturing bisazo compound | RICOH COMPANY, LTD. (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20080096117-A1 | Bisazo compound, 2-hydroxy-3-phenylcarbamoyl naphthalene compound and method manufacturing bisazo compound | RICOH COMPANY, LTD. | 2008-04-24 | — | — | US | disclosed |
| US-20080096117-A1 | Bisazo compound, 2-hydroxy-3-phenylcarbamoyl naphthalene compound and method manufacturing bisazo compound | RICOH COMPANY, LTD. | 2008-04-24 | — | — | US | disclosed |
| US-4871633-A | PHOTOELECTRICAL CHARGE GENERATING COMPOUND | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4618672-A | Bisazo compounds useful as charge generating pigments in electrophotography | RICOH COMPANY, LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| US-4314015-A | Electrophotographic sensitive materials containing disazo compounds | RICOH CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4299896-A | Electrophotographic sensitive materials containing a disazo pigment | RICOH CO., LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096117-A1 | Bisazo compound, 2-hydroxy-3-phenylcarbamoyl naphthalene compound and method manufacturing bisazo compound | AHR, PBRM1, AR | KDM4E 1277/4885HPGD 3355/4885ESR1 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.