Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051561 | 0.84 | MAPT (0.42) | TSHRMAPTHTTMEN1KMT2A | |
| SCHEMBL5059411 | 0.81 | TSHR (0.38) | TSHRMAPTHTTMEN1KMT2A | |
| SCHEMBL5010543 | 0.78 | PGK1 (0.52) | TSHRMAPTHTTPPARDNPY5R | |
| SCHEMBL7141295 | 0.77 | PDE10A (0.37) | TDP1MEN1NR1I2KMT2AALDH1A1 | |
| SCHEMBL4133793 | 0.76 | MAPT (0.39) | TSHRMAPTHTTTDP1TP53 | |
| SCHEMBL2022499 | 0.75 | TSHR (0.39) | TSHRMAPTHTTTDP1TP53 | |
| SCHEMBL31039235 | 0.75 | TSHR (0.39) | TSHRMAPTHTTTDP1TP53 | |
| SCHEMBL13640341 | 0.75 | MAPT (0.35) | TSHRMAPTHTTTDP1TP53 | |
| SCHEMBL26999125 | 0.74 | KMT2A (0.35) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL30669248 | 0.71 | PGK1 (0.41) | TSHRNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030072-A1 | COMPOUND FOR INHIBITING THE FORMATION OF BETA-AMYLOID FIBRIL, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-03-13 | — | — | WO | disclosed |