Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133793 | 0.91 | MAPT (0.39) | MAPTHTTTSHRNOS3NOS2 | |
| SCHEMBL5052076 | 0.84 | TSHR (0.39) | MAPTHTTTSHRPPARDEGFR | |
| SCHEMBL5059411 | 0.82 | TSHR (0.38) | MAPTHTTTSHRPPARDEGFR | |
| SCHEMBL5010543 | 0.79 | PGK1 (0.52) | MAPTHTTTSHRKDM4EPPARD | |
| SCHEMBL28565161 | 0.76 | MAPT (0.43) | MAPTHTTTSHRKDM4EPPARD | |
| SCHEMBL23714033 | 0.74 | MAPT (0.39) | MAPTHTTTSHRKDM4EPPARD | |
| SCHEMBL1107431 | 0.74 | SMN1; SMN2 (0.40) | MAPTHTTTSHRMEN1GAA | |
| SCHEMBL17017353 | 0.74 | KDM4E (0.54) | MAPTHTTTSHRNOS3NOS2 | |
| SCHEMBL9863809 | 0.74 | MAPT (0.42) | MAPTHTTTSHRMEN1KMT2A | |
| SCHEMBL1107397 | 0.71 | TSHR (0.38) | MAPTHTTTSHRKDM4EPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030072-A1 | COMPOUND FOR INHIBITING THE FORMATION OF BETA-AMYLOID FIBRIL, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-03-13 | — | — | WO | disclosed |