SCHEMBL5052085

SCHEMBL5052085

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nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TDP1 Q9NUW8 3/20 0.56
KDM4E B2RXH2 2/20 0.40
PDE4A P27815 1/20 0.40
ALDH1A1 P00352 2/20 0.38
NR1I2 O75469 1/20 0.38
CYP1A2 P05177 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5028006 1.00 LMNA (0.59) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL756618 1.00 LMNA (0.59) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL5051917 1.00 LMNA (0.59) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL521727 0.94 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL5133813 0.94 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL10620808 0.94 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL20239632 0.87 LMNA (0.39) LMNAL3MBTL1TDP1ALDH1A1NR1I2
Xylitol SCHEMBL4599492 0.83 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL5273838 0.83 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Adonitol SCHEMBL20594035 0.83 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1952919-A2 Magnetic nanoparticles and aqueous colloid composition containing the same Fujifilm Corporation (JP) 2008-08-06 EP disclosed