SCHEMBL10620808

SCHEMBL10620808

OCC(O)C(O)C(O)C(O)CS

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
TDP1 Q9NUW8 2/20 0.65
KDM4E B2RXH2 2/20 0.46
PDE4A P27815 1/20 0.46
USP2 O75604 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
ALDH1A1 P00352 3/20 0.38
NR1I2 O75469 1/20 0.38
CYP1A2 P05177 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPT P10636 1/20 0.33
TOP1 P11387 1/20 0.32
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL521727 1.00 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL5133813 1.00 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL5051917 0.94 LMNA (0.59) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL5028006 0.94 LMNA (0.59) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL5052085 0.94 LMNA (0.59) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL756618 0.94 LMNA (0.59) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL20239655 0.87 LMNA (0.44) LMNAL3MBTL1TDP1ALDH1A1NR1I2
Mannitol SCHEMBL23066399 0.83 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL2477078 0.83 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL2297640 0.83 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066288-B Method for coupling ligands to composite materials 默克密理博有限公司 2025-03-11 CN claimed
US-20220410076-A1 METHODS FOR COUPLING A LIGAND TO A COMPOSITE MATERIAL MERCK MILLIPORE LTD. (IE) 2022-12-29 US claimed
EP-4061515-A1 METHODS FOR COUPLING A LIGAND TO A COMPOSITE MATERIAL Merck Millipore Ltd. (IE) 2022-09-28 EP claimed
CN-115066288-A Method for coupling ligands to composite materials 默克密理博有限公司 2022-09-16 CN claimed
US-20210161789-A1 HETEROCYCLIC-DITHIOL CLICK CHEMISTRY UNIV NORTHEASTERN (US) 2021-06-03 US claimed
WO-2021099522-A1 METHODS FOR COUPLING A LIGAND TO A COMPOSITE MATERIAL MERCK MILLIPORE LTD. (IE) 2021-05-27 WO claimed
EP-3778001-A1 CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS Merck Millipore Ltd. (IE) 2021-02-17 EP claimed
CN-111278508-A Heterocyclic dithiol click chemistry 东北大学 2020-06-12 CN claimed
EP-3259050-B1 CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS MERCK MILLIPORE LTD (IE) 2020-06-10 EP claimed
EP-3651854-A1 HETEROCYCLIC-DITHIOL CLICK CHEMISTRY Northeastern University (US) 2020-05-20 EP claimed
CN-102058525-A Lamivudine injection and preparation method thereof Tianjin jinshi pharmaceutical co ltd 2011-05-18 CN claimed
CN-102028653-A Injection administration preparation containing lamivudine TIANJIN PACIFIC PHARMACEUTICAL 2011-04-27 CN claimed
CN-101756890-A Parenteral preparation containing active entecavir and preparation method thereof TIANJIN PACIFIC PHARMACEUTICAL 2010-06-30 CN claimed
CN-101756891-A Cladribine preparation administrated by injection and preparation method thereof TIANJIN PACIFIC PHARMACEUTICAL 2010-06-30 CN claimed
CN-101444478-A Injection preparation containing active constituent adefovir dipivoxil and preparation method thereof TIANJIN JINGUIGU XYLITOL CO LT (CN) 2009-06-03 CN claimed
CN-101444490-A Injection preparation containing anhydrogalactitol and preparation method thereof TIANJIN JINGUIGU XYLITOL CO LT (CN) 2009-06-03 CN claimed
CN-1299668-C Nanometer realgar solid dispersion and its preparation method UNIV HUAZHONG SCIENCE TECH (CN) 2007-02-14 CN claimed
CN-1245975-C Medicinal composition for stabilizing delotadine in preparation TIANJIN MEDICINE ACADEMY (CN) 2006-03-22 CN claimed
CN-1552324-A Medicinal composition for stabilizing delotadine in preparation 天津药物研究院 2004-12-08 CN claimed
CN-1478486-A Nanometer realgar solid dispersion and its preparation method 华中科技大学 2004-03-03 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210161789-A1 HETEROCYCLIC-DITHIOL CLICK CHEMISTRY TST, TMT1A, MTHFD2 LMNA 4392/4885L3MBTL1 3408/4885TDP1 618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.