SCHEMBL5052149

SCHEMBL5052149

Cc1[c]c(C)cc(C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 3/20 0.56
HCAR1 Q9BXC0 1/20 0.48
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA14 Q9ULX7 3/20 0.46
NOTUM Q6P988 1/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CA3 P07451 2/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 2/20 0.44
CA5A P35218 2/20 0.44
CA5B Q9Y2D0 2/20 0.44
TP53 P04637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1637909 0.79 CA5A (0.50) TPMTSMN1; SMN2CA5ALMNAMAPT
SCHEMBL1971878 0.77 PARP1 (0.45) CA1CA2ALDH1A1SMN1; SMN2MAPT
Methyl Alcohol SCHEMBL27916105 0.74 TPMT (0.63) TPMTHCAR1CA12CA1CA2
SCHEMBL4195251 0.73 HDAC6 (0.45) CA2ALDH1A1SMN1; SMN2HPGDTSHR
SCHEMBL4200023 0.73 CA1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL4187982 0.73 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL22982 0.73 CA12 (0.65) TPMTHCAR1CA12CA1CA2
SCHEMBL26189 0.73 CA12 (0.65) TPMTHCAR1CA12CA1CA2
SCHEMBL40661 0.72 TPMT (0.89) TPMTHCAR1CA12CA1CA2
SCHEMBL221684 0.72 TPMT (1.00) TPMTHCAR1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5702887-A BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS CHIRON DIAGNOSTICS CORPORATION (US) 1997-12-30 US claimed
EP-1946108-A2 HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY Bayer Healthcare LLC (US) 2008-07-23 EP disclosed
WO-2006130736-A2 HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS (US) 2006-12-07 WO disclosed
US-5879894-A DETECTION AND/OR QUANTITATION OF AT LEAST TWO SUBSTANCES IN A TEST SAMPLE; APPLICATION IN CLINICAL DIAGNOSTICS CHIRON DIAGNOSTICS CORPORATION (US) 1999-03-09 US disclosed
US-5702887-A BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS CHIRON DIAGNOSTICS CORPORATION (US) 1997-12-30 US disclosed