Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 16/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 11/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084331 | 0.79 | MAPK14 (0.40) | GRNSORT1MAPK14MAPK13MAPK12 | |
| SCHEMBL2025620 | 0.78 | MAPK14 (0.48) | GRNSORT1MAPK14MAPK13MAPK12 | |
| SCHEMBL2082236 | 0.77 | MAPK14 (0.42) | GRNSORT1MAPK14MAPK13MAPK12 | |
| SCHEMBL5052142 | 0.77 | MAPK14 (0.45) | GRNSORT1MAPK14MAPK13MAPK12 | |
| SCHEMBL2082586 | 0.76 | RAB9A (0.42) | GRNSORT1MAPK14MAPK13MAPK12 | |
| SCHEMBL2084328 | 0.75 | MAPK14 (0.42) | GRNSORT1MAPK14MAPK13MAPK12 | |
| SCHEMBL2081248 | 0.75 | CYP1A2 (0.40) | GRNSORT1MAPK14MAPK13MAPK12 | |
| SCHEMBL2084854 | 0.74 | CDC25B (0.43) | MAPK14MAPK9CDK8 | |
| SCHEMBL2025289 | 0.74 | HPGD (0.43) | GRNSORT1MAPK14MAPK13MAPK12 | |
| Hydrochloric Acid SCHEMBL2025286 | 0.73 | HPGD (0.42) | GRNSORT1MAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | ABL2, BRAF, MAP3K1 | GRN 3157/4885SORT1 4054/4885MAPK14 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.