Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637349 | 0.90 | L3MBTL1 (0.50) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL5056708 | 0.84 | AHR (0.54) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL5052363 | 0.80 | MAPT (0.56) | BLMPMP22KCNH2CYP3A4TSHR | |
| SCHEMBL5054998 | 0.75 | SMN1; SMN2 (0.39) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11473546 | 0.74 | MAPT (0.40) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11721606 | 0.72 | SMN1; SMN2 (0.43) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11471392 | 0.72 | NPC1 (0.40) | SMN1; SMN2KMT2AMAPTLMNAKCNN4 | |
| SCHEMBL8283520 | 0.72 | MAPT (0.52) | BLMSLC22A2SLC22A1PGRTHRB | |
| SCHEMBL2465434 | 0.72 | SMN1; SMN2 (0.50) | BLMSLC22A2SLC22A1PGRTHRB | |
| Urea SCHEMBL28161295 | 0.71 | SMN1; SMN2 (0.54) | BLMSLC22A2SLC22A1PGRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | 7TM PHARMA A/S (DK) | 2008-05-22 | — | — | US | disclosed |
| US-4379158-A | Antisecretory imidazole amidine compounds, composition and method of use | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | HRH1, HRH2, HRH3 | BLM 3183/4885SLC22A2 1742/4885SLC22A1 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.