Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | PKM | P14618 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052302 | 0.84 | BLM (0.48) | SMN1; SMN2MAPTKMT2AMEN1KDM4E | |
| SCHEMBL5060670 | 0.81 | KIF11 (0.50) | RAB9ANPC1SMN1; SMN2CDK5CDK5R1 | |
| SCHEMBL28637349 | 0.81 | L3MBTL1 (0.50) | RAB9ANPC1PKMSMN1; SMN2KMT2A | |
| SCHEMBL5062197 | 0.81 | CA1 (0.52) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11632086 | 0.75 | AHR (0.57) | AHRF2RAB9ANPC1PKM | |
| SCHEMBL15854868 | 0.74 | AHR (0.81) | AHRF2RAB9ANPC1PKM | |
| SCHEMBL31480846 | 0.74 | AHR (0.67) | AHRF2RAB9ANPC1PKM | |
| SCHEMBL11721606 | 0.74 | SMN1; SMN2 (0.43) | AHRRAB9ANPC1SMN1; SMN2CDK5 | |
| SCHEMBL11881295 | 0.74 | KMT2A (0.44) | AHRHPGDMAPTKMT2AMEN1 | |
| SCHEMBL29060870 | 0.72 | AHR (0.60) | AHRF2RAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | 7TM PHARMA A/S (DK) | 2008-05-22 | — | — | US | disclosed |
| EP-1758874-A1 | SUBSTITUTED THIAZOLEACETIC ACIDS AS CRTH2 LIGANDS | 7TM Pharma A/S (DK) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005116001-A1 | SUBSTITUTED THIAZOLEACETIC AS CRTH2 LIGANDS | 7TM PHARMA A/S (DK) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119456-A1 | Substituted Thiazoleacetic Acid as Crth2 Ligands | HRH1, HRH2, HRH3 | AHR 63/4885F2 3909/4885RAB9A 2363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.