Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.39 |
| ▸ | BRD1 | O95696 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL27905058 | 0.78 | CA1 (0.43) | TDP1ALDH1A1MAPK1TSHRCA1 | |
| SCHEMBL6291051 | 0.77 | TSHR (0.46) | HTTSMN1; SMN2SLC6A4L3MBTL1LMNA | |
| Sulfuric Acid SCHEMBL27904947 | 0.77 | CA1 (0.41) | TDP1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL3796273 | 0.77 | HTT (0.50) | HTTSMN1; SMN2FFAR1L3MBTL1TDP1 | |
| SCHEMBL2608310 | 0.73 | HTT (0.65) | HTTSMN1; SMN2HTR2ASLC6A4L3MBTL1 | |
| Sulfuric Acid SCHEMBL3800614 | 0.72 | HTT (0.51) | HTTSMN1; SMN2L3MBTL1TDP1LMNA | |
| SCHEMBL3312703 | 0.72 | CYP3A4 (0.43) | HTTSMN1; SMN2HTR2ASLC6A4L3MBTL1 | |
| Sulfuric Acid SCHEMBL5676715 | 0.71 | HTT (0.47) | HTTSMN1; SMN2FFAR1L3MBTL1TDP1 | |
| SCHEMBL16621785 | 0.71 | HTT (0.70) | HTTSMN1; SMN2FFAR1HTR2ASLC6A4 | |
| SCHEMBL11585106 | 0.69 | ALDH1A1 (0.60) | HTTSMN1; SMN2FFAR1HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057070-A2 | TYPE SEPARATION OF SINGLE-WALLED CARBON NANOTUBES VIA PHASE TRANSFER | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-05-15 | — | — | WO | disclosed |