SCHEMBL2608310

SCHEMBL2608310

Cc1ccc(Oc2ccccc2Oc2ccc(C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.65
ALDH1A1 P00352 4/20 0.65
MAPK1 P28482 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
HTR2A P28223 2/20 0.60
SLC6A4 P31645 2/20 0.60
LMNA P02545 1/20 0.58
TEAD4 Q15561 1/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
POLB P06746 2/20 0.50
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ACHE P22303 1/20 0.48
AR P10275 1/20 0.47
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11585106 0.95 ALDH1A1 (0.60) HTTALDH1A1MAPK1L3MBTL1HTR2A
SCHEMBL29377831 0.91 HTT (0.83) HTTALDH1A1MAPK1L3MBTL1HTR2A
SCHEMBL6444082 0.91 HTT (0.83) HTTALDH1A1MAPK1L3MBTL1HTR2A
SCHEMBL172615 0.88 HTR2A (0.55) HTTALDH1A1MAPK1L3MBTL1HTR2A
SCHEMBL28604976 0.86 HTR2A (0.53) HTTALDH1A1MAPK1L3MBTL1HTR2A
SCHEMBL8591053 0.85 HTR2A (0.56) HTTALDH1A1MAPK1L3MBTL1HTR2A
SCHEMBL3179793 0.84 LMNA (0.54) HTTALDH1A1MAPK1L3MBTL1HTR2A
SCHEMBL5023569 0.84 SLC6A4 (0.51) HTTALDH1A1MAPK1L3MBTL1HTR2A
SCHEMBL9046668 0.84 HTR2A (0.54) HTTALDH1A1MAPK1L3MBTL1HTR2A
SCHEMBL4266095 0.84 HTR2A (0.51) HTTALDH1A1MAPK1L3MBTL1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11345180-B2 Display medium for assessment and method for manufacturing same ZEON CORPORATION (JP) 2022-05-31 US disclosed
US-10457780-B2 Hygromorphic polymers and copolymers having humidity-driven motility UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2019-10-29 US disclosed
US-20190184732-A1 DISPLAY MEDIUM FOR ASSESSMENT AND METHOD FOR MANUFACTURING SAME ZEON CORPORATION (JP) 2019-06-20 US disclosed
US-10301430-B2 Bis(azobenzene) diamines and photomechanical polymers made therefrom THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2019-05-28 US disclosed
US-10246556-B2 Polyimide polymer and polyimide film TAIFLEX SCIENTIFIC CO., LTD. (TW) 2019-04-02 US disclosed
US-20180194898-A1 HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2018-07-12 US disclosed
US-20180194898-A1 HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2018-07-12 US disclosed
US-9932445-B2 Hygromorphic polymers and copolymers having humidity-driven motility THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2018-04-03 US disclosed
US-9896545-B2 Bis(azobenzene) diamines and photomechanical polymers made therefrom THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2018-02-20 US disclosed
US-20180022872-A1 BIS(AZOBENZENE) DIAMINES AND PHOTOMECHANICAL POLYMERS MADE THEREFROM GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2018-01-25 US disclosed
US-20110140041-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS ZEON CORPORATION (JP) 2011-06-16 US disclosed
EP-2295477-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTAL POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS Zeon Corporation (JP) 2011-03-16 EP disclosed
US-20100323161-A1 HIGHLY ADHESIVE POLYIMIDE COPPER CLAD LAMINATE AND METHOD OF MAKING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-12-23 US disclosed
US-20100323161-A1 HIGHLY ADHESIVE POLYIMIDE COPPER CLAD LAMINATE AND METHOD OF MAKING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-12-23 US disclosed
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE ZEON CORPORATION (JP) 2010-10-14 US disclosed
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE ZEON CORPORATION (JP) 2010-10-14 US disclosed
EP-2143710-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORPORATION (JP) 2010-01-13 EP disclosed
WO-2009099918-A1 HIGHLY ADHESIVE POLYIMIDE COPPER CLAD LAMINATE AND METHOD OF MAKING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-13 WO disclosed
US-20090197104-A1 HIGHLY ADHESIVE POLYIMIDE COPPER CLAD LAMINATE AND METHOD OF MAKING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-06 US disclosed
US-20090197104-A1 HIGHLY ADHESIVE POLYIMIDE COPPER CLAD LAMINATE AND METHOD OF MAKING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10301430-B2 Bis(azobenzene) diamines and photomechanical polymers made therefrom WASF2, PBRM1, WEE1 HTT 2593/4885ALDH1A1 1473/4885MAPK1 2893/4885
US-20110140041-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS CCNB1, CCNT1, CCNB2 HTT 4423/4885ALDH1A1 1445/4885MAPK1 561/4885
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE LEO1, ZYX, CCNT1 HTT 4719/4885ALDH1A1 2720/4885MAPK1 778/4885
US-20180194898-A1 HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY DNAH12, PARG, PARN HTT 223/4885ALDH1A1 2805/4885MAPK1 2432/4885
US-10457780-B2 Hygromorphic polymers and copolymers having humidity-driven motility DNAH12, PARG, PARN HTT 223/4885ALDH1A1 2805/4885MAPK1 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.