SCHEMBL505319

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL504195	0.86	ACHE (0.57)	ALDH1A1SMN1; SMN2RAB9AKDM4EMAPT
	SCHEMBL504886	0.85	GPR119 (0.53)	GRM5ACHEBACE1BCHEGPR119
	SCHEMBL504871	0.82	GRM5 (0.67)	GRM5ACHEBACE1GPR119
	SCHEMBL10250911	0.82	GRM5 (0.46)	KDM4EMAPTGRM5ACHEBACE1
	SCHEMBL504960	0.81	GRM5 (0.65)	ALDH1A1SMN1; SMN2RAB9AKDM4EMAPT
	SCHEMBL10250005	0.80	GRM5 (0.52)	ALDH1A1SMN1; SMN2LMNARAB9AKDM4E
	SCHEMBL505152	0.78	ACHE (0.55)	LMNAGRM5ACHEBACE1BCHE
	SCHEMBL505316	0.78	ACHE (0.57)	ALDH1A1SMN1; SMN2MAPK1RAB9AKDM4E
	SCHEMBL504579	0.78	GRM5 (0.65)	ALDH1A1SMN1; SMN2RAB9AKDM4EGRM5
	SCHEMBL10285696	0.76	GRM5 (0.47)	ALDH1A1SMN1; SMN2RAB9AKDM4EGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.