Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052875 | 0.80 | CYP2D6 (0.40) | CYP2D6LMNATSHRKMT2AHPGD | |
| SCHEMBL5053234 | 0.75 | CYP2D6 (0.41) | CYP2D6TSHR | |
| SCHEMBL27862589 | 0.71 | CYP2D6 (0.47) | CYP2D6ALOX5IDO1TDO2LMNA | |
| SCHEMBL8461609 | 0.71 | CYP2D6 (0.41) | CYP2D6ALOX5IDO1TDO2LMNA | |
| SCHEMBL5060151 | 0.71 | ALOX5 (0.37) | ALOX5IDO1TDO2KMT2AHDAC3 | |
| SCHEMBL5053070 | 0.71 | IDO1 (0.38) | ALOX5IDO1TDO2LMNAHDAC3 | |
| SCHEMBL5053096 | 0.71 | POLB (0.41) | ALOX5IDO1TDO2HPGD | |
| SCHEMBL5511566 | 0.70 | ALOX5 (0.49) | CYP2D6ALOX5IDO1TDO2LMNA | |
| SCHEMBL8461492 | 0.69 | CYP2D6 (0.39) | CYP2D6ALOX5IDO1TDO2KMT2A | |
| SCHEMBL8458472 | 0.68 | CYP2D6 (0.47) | CYP2D6ALOX5IDO1TDO2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080311037-A1 | Compounds which bind PSMA and uses thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311037-A1 | Compounds which bind PSMA and uses thereof | FOLH1, PSMA1, BPHL | CYP2D6 2882/4885ALOX5 4088/4885IDO1 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.