Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TDO2 | P48775 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GABRP | O00591 | 1/20 | 0.58 |
| ▸ | GABRD | O14764 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060136 | 0.83 | TDO2 (0.63) | KDM4ETDO2MEN1MAPTKMT2A | |
| SCHEMBL11490695 | 0.83 | KDM4E (0.71) | KDM4ETDO2MEN1MAPTKMT2A | |
| SCHEMBL28505445 | 0.80 | DYRK1A (0.78) | KDM4EMAOAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2721049 | 0.80 | KDM4E (0.68) | KDM4ETDO2MEN1MAPTKMT2A | |
| SCHEMBL10642447 | 0.79 | KDM4E (0.58) | KDM4ETDO2MEN1MAPTKMT2A | |
| SCHEMBL27917573 | 0.77 | KDM4E (0.59) | KDM4ETDO2MEN1MAPTKMT2A | |
| SCHEMBL5785176 | 0.77 | KDM4E (0.68) | KDM4ETDO2MEN1MAPTKMT2A | |
| SCHEMBL27905044 | 0.77 | KDM4E (0.75) | KDM4ETDO2MEN1MAPTKMT2A | |
| SCHEMBL23319492 | 0.76 | TDO2 (0.63) | KDM4ETDO2MEN1MAPTKMT2A | |
| SCHEMBL30518089 | 0.76 | TDO2 (0.63) | KDM4ETDO2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132454-A1 | CARBOLINES AND THEIR USE AS IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2008-11-06 | — | — | WO | disclosed |