⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630281 | 0.79 | — | — | |
| SCHEMBL23904 | 0.65 | — | — | |
| SCHEMBL19001418 | 0.62 | — | — | |
| SCHEMBL1150 | 0.55 | — | — | |
| SCHEMBL146255 | 0.55 | — | — | |
| SCHEMBL449059 | 0.55 | — | — | |
| SCHEMBL1870256 | 0.55 | — | — | |
| SCHEMBL1865631 | 0.55 | — | — | |
| SCHEMBL15284592 | 0.53 | — | — | |
| SCHEMBL978361 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166660-A1 | KRAS G12C INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2024-05-23 | — | — | US | claimed |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2023-10-12 | — | — | US | claimed |
| US-20220389021-A1 | INHIBITORS OF KRAS G12C | BEONE MEDICINES I GMBH (CH) | 2022-12-08 | — | — | US | claimed |
| CN-114929706-A | Inhibitors of KRAS G12C | 百济神州有限公司 | 2022-08-19 | — | — | CN | claimed |
| WO-2022152233-A1 | KRAS G12C INHIBITORS | BEIGENE, LTD. (KY) | 2022-07-21 | — | — | WO | claimed |
| WO-2021058018-A1 | INHIBITORS OF KRAS G12C | BEIGENE, LTD. (KY) | 2021-04-01 | — | — | WO | claimed |
| CN-109705063-B | Entecavir intermediate and synthetic method thereof, and synthetic method of entecavir | 广州市朗启医药科技有限责任公司 | 2021-01-01 | — | — | CN | claimed |
| EP-3275972-B1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2019-06-19 | — | — | EP | claimed |
| EP-3495343-A1 | POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2019-06-12 | — | — | EP | claimed |
| US-20190169502-A1 | POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2019-06-06 | — | — | US | claimed |
| WO-1996025406-A1 | FUNGICIDAL AZA-HETEROCYCLOALKENES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | claimed |
| WO-1996022983-A1 | SUBSTITUTED ARYLAZADIOXACYCLO ALKENE FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-01 | — | — | WO | claimed |
| EP-0560407-B1 | Pharmaceutically active compounds | SCHERING CORP (US) | 1996-05-22 | — | — | EP | claimed |
| US-5374416-A | Nitrogenous macrocyclic ligands, polymetallic complexes and diagnostic and therapeutic composition | GUERBET S.A. (FR) | 1994-12-20 | — | — | US | claimed |
| EP-0274867-B1 | Pharmaceutically active compounds | SCHERING CORP (US) | 1994-04-13 | — | — | EP | claimed |
| EP-0560407-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-09-15 | — | — | EP | claimed |
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | claimed |
| EP-0407217-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1991-01-09 | — | — | EP | claimed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | claimed |
| US-3971809-A | 3A,4,7,7A-Tetrahydro-4-phenylethyl-7a-alkyl-5(6H)-indanones and process for the preparation thereof | HOFFMANN-LA ROCHE INC. (US) | 1976-07-27 | — | — | US | claimed |