Pyruvate

Pyruvate

SCHEMBL5054355

CC(=O)C(=O)O.COC(=O)C(C)=O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
EGLN1 Q9GZT9 1/20 0.39
TSHR P16473 3/20 0.35
THPO P40225 1/20 0.35
FFAR3 O14843 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
GAA P10253 2/20 0.35
MGAM O43451 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
POLB P06746 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
DNMT1 P26358 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL28038876 0.94
SCHEMBL27432 0.90
SCHEMBL27817051 0.87
SCHEMBL4633009 0.87
SCHEMBL4632179 0.87
SCHEMBL27475050 0.87
Ammonia Solution, Strong SCHEMBL29165044 0.84
Cyclopropane SCHEMBL27492181 0.81 ALDH1A1 (0.48) ALDH1A1EGLN1TSHRTHPOGAA
SCHEMBL468496 0.80 ALDH1A1 (0.37) ALDH1A1EGLN1FFAR3GAAMGAM
SCHEMBL28868431 0.79 ALDH1A1 (0.52) ALDH1A1EGLN1TSHRTHPOGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1986665-A2 MICROALGAE-DERIVED COMPOSITIONS FOR IMPROVING THE HEALTH AND APPEARANCE OF SKIN Solazyme, Inc. (US) 2008-11-05 EP disclosed
WO-2007084769-A2 MICROALGAE-DERIVED COMPOSITIONS FOR IMPROVING THE HEALTH AND APPEARANCE OF SKIN SOLAZYME, INC. (US) 2007-07-26 WO disclosed
EP-1161518-A2 TOWELETTE PRODUCT UNILEVER PLC (GB) 2001-12-12 EP disclosed
WO-2000056271-A2 TOWELETTE PRODUCT UNILEVER PLC (GB) 2000-09-28 WO disclosed