SCHEMBL5055092

SCHEMBL5055092

CC(C)(C)Sc1ccc(-c2c(F)c(F)c(F)c(F)c2F)cc1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.39
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 1/20 0.36
AR P10275 1/20 0.35
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5052581 0.92 SLC6A4 (0.37) SLC6A4KDM4EHSD17B10AR
SCHEMBL5051548 0.90 SLC6A4 (0.36) SLC6A4KDM4EHSD17B10AR
SCHEMBL5051482 0.79 SLC6A4 (0.32) SLC6A4
SCHEMBL14189682 0.78 HSD17B10 (0.35) SLC6A4HSD17B10
SCHEMBL5052526 0.76 MGAM (0.34)
SCHEMBL7937564 0.75 SLC6A4 (0.45) SLC6A4KDM4EHSD17B10ARALDH1A1
SCHEMBL4159679 0.74 TTR (0.32)
SCHEMBL12762364 0.71 KIF11 (0.46) KDM4EALDH1A1
SCHEMBL10300260 0.71 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL5051483 0.70 ALDH1A1 (0.42) SLC6A4KDM4EHSD17B10ARALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080138635-A1 Conjugated Organic Molecules for Molecular Electronic Devices NATIONAL UNIVERSITY OF SINGAPORE (SG) 2008-06-12 US disclosed
US-20080138635-A1 Conjugated Organic Molecules for Molecular Electronic Devices NATIONAL UNIVERSITY OF SINGAPORE (SG) 2008-06-12 US disclosed
WO-2006093467-A1 CONJUGATED ORGANIC MOLECULES FOR MOLECULAR ELECTRONIC DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-09-08 WO disclosed