SCHEMBL5056936

SCHEMBL5056936

CC(C)(C)OC(=O)CCCSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SLC17A5 Q9NRA2 1/20 0.51
▸ MDM2 Q00987 3/20 0.51
▸ MDM4 O15151 2/20 0.48
▸ TP53 P04637 2/20 0.48
▸ TLR2 O60603 2/20 0.47
▸ PPARG P37231 3/20 0.46
▸ PPARA Q07869 3/20 0.46
▸ PPARD Q03181 2/20 0.45
▸ CASP3 P42574 1/20 0.44
▸ TNF P01375 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30393072 1.00 SLC17A5 (0.51) SLC17A5MDM2MDM4TP53TLR2
SCHEMBL5056933 1.00 SLC17A5 (0.51) SLC17A5MDM2MDM4TP53TLR2
SCHEMBL17079665 0.94 SLC17A5 (0.53) SLC17A5MDM2MDM4TP53TLR2
SCHEMBL9514163 0.93 PPARG (0.51) SLC17A5MDM2MDM4TP53TLR2
SCHEMBL17079649 0.89 SLC17A5 (0.55) SLC17A5MDM2MDM4TP53TLR2
SCHEMBL29456972 0.89 SLC17A5 (0.51) SLC17A5MDM2MDM4TP53TLR2
SCHEMBL5060916 0.89 SMN1; SMN2 (0.46) SLC17A5MDM2MDM4TP53CASP3
SCHEMBL5274394 0.89 SMN1; SMN2 (0.46) SLC17A5MDM2MDM4TP53CASP3
SCHEMBL5060915 0.89 SMN1; SMN2 (0.46) SLC17A5MDM2MDM4TP53CASP3
SCHEMBL5416534 0.88 SLC17A5 (0.51) SLC17A5MDM2MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509502-B2 Hybrid immunoglobulin containing nonpeptidyl linkage BIOMOLECULAR HOLDINGS LLC (US) 2025-12-30 — — US disclosed
EP-4169944-A1 PROCESS FOR PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Biomolecular Holdings LLC (US) 2023-04-26 — — EP disclosed
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-09-01 — — US disclosed
EP-4039281-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Biomolecular Holdings LLC (US) 2022-08-10 — — EP disclosed
EP-3701971-B1 COMPOUNDS USEFUL IN PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-07-06 — — EP disclosed
US-11220556-B2 Hybrid immunoglobulin containing non-peptidyl linkage BIOMOLECULAR HOLDINGS LLC (US) 2022-01-11 — — US disclosed
EP-3611180-B1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2021-12-22 — — EP disclosed
US-20210340222-A1 HYBRID IMMUNOGLOBULIN CONTAINING NONPEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2021-11-04 — — US disclosed
US-11066459-B2 Hybrid immunoglobulin containing non-peptidyl linkage BIOMOLECULAR HOLDINGS LLC (US) 2021-07-20 — — US disclosed
EP-3701971-A1 COMPOUNDS USEFUL IN PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2020-09-02 — — EP disclosed
EP-3116486-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2017-01-18 — — EP disclosed
US-20170008950-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC 2017-01-12 — — US disclosed
US-20160024226-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC 2016-01-28 — — US disclosed
EP-2968495-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2016-01-20 — — EP disclosed
WO-2015138907-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE CAPON DANIEL J (US) 2015-09-17 — — WO disclosed
WO-2014144911-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE CAPON DANIEL J (US) 2014-09-18 — — WO disclosed
US-20080004290-A1 Anti-Cancer Agents THE UNIVERSITY OF QUEENSLAND (AU) 2008-01-03 — — US disclosed
EP-1694640-A4 ANTI-CANCER AGENTS UNIV QUEENSLAND (AU) 2007-01-10 — — EP disclosed
EP-1694640-A1 ANTI-CANCER AGENTS THE UNIVERSITY OF QUEENSLAND (AU) 2006-08-30 — — EP disclosed
WO-2005051901-A1 ANTI-CANCER AGENTS THE UNIVERSITY OF QUEENSLAND (AU) 2005-06-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066459-B2 Hybrid immunoglobulin containing non-peptidyl linkage FCGR3B, FCGR2A, SCLY SLC17A5 158/4885MDM2 4485/4885MDM4 4458/4885
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, FCGR2A, VSIG8 SLC17A5 795/4885MDM2 4693/4885MDM4 4598/4885
US-11220556-B2 Hybrid immunoglobulin containing non-peptidyl linkage FCGR3B, FCGR2A, VSIG8 SLC17A5 1678/4885MDM2 4396/4885MDM4 3802/4885
US-20210340222-A1 HYBRID IMMUNOGLOBULIN CONTAINING NONPEPTIDYL LINKAGE FCGR3B, FCGR2A, SCLY SLC17A5 99/4885MDM2 4233/4885MDM4 4458/4885
US-20160024226-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, FCGR2A, VSIG8 SLC17A5 795/4885MDM2 4693/4885MDM4 4598/4885
US-20170008950-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, SCLY, FCGR2A SLC17A5 202/4885MDM2 4483/4885MDM4 4416/4885
US-12509502-B2 Hybrid immunoglobulin containing nonpeptidyl linkage FCGR2A, FCGR3B, CD74 SLC17A5 635/4885MDM2 3930/4885MDM4 4781/4885
US-20080004290-A1 Anti-Cancer Agents TP53, TOP2A, MCL1 SLC17A5 1418/4885MDM2 1432/4885MDM4 611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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